CL ISOBTR CL ISOBTR

Synonyms

Allscripts (AEHR) Order Name

Isoagglutinin Titer, Anti-B

Sunrise Clinical Manager (SCM) Order Name

Isoagglutinin Titer, Anti-B

EPIC Order Name

Isoagglutinin Titer, Anti-B

Clinical Info

Isoagglutinins are antibodies produced by an individual that cause agglutination of RBCs in other individuals. People possess isoagglutinins directed toward the A or B antigen absent from their own RBCs. For example, type A or O individuals will usually possess anti-B. The anti-B is formed in response to exposure to B-like antigenic structures found in ubiquitous non-red cell biologic entities (eg, bacteria).

Isoagglutinins present in the newborn are passively acquired from maternal circulation. Such passively acquired isoagglutinins will gradually disappear, and the infant will begin to produce isoagglutinins at 3 to 6 months of age.

Isoagglutinin production may vary in patients with certain pathologic conditions. Decreased levels of isoagglutinins may be seen in patients with acquired and congenital hypogammaglobulinemia and agammaglobulinemia.

Specimen Type

Blood

Container

Pink Top Tube

Collection Instructions

Container/Tube: Serum Red top / Pink-top (K2 EDTA) tube - Plasma gel tube and Yellow ACD tube are not acceptable.
Specimen: Full tube
Transport Temperature: Ambient preferred / Refrigerated
Note: Patient’s name, date of birth, time of collection required on tube for processing.

Transport Instructions

Ambient preferred / Refrigerated

Specimen Stability

Methodology

Hemagglutination

Days Performed

Performing Laboratory

Northwell Health Laboratories

CPT

86886
LOINC Code: 34464-8

PDM

2160437

Result Interpretation

Forms