ADBIO ADBIO

Synonyms

Allscripts (AEHR) Order Name

Alzheimers Disease Eval, CSF

Sunrise Clinical Manager (SCM) Order Name

Alzheimers Disease Eval, CSF

EPIC Order Name

CSF, Alzheimer Disease Evaluation

Clinical Info

Assessment of adults with cognitive impairment being evaluated for Alzheimer disease (AD) and other causes of 
cognitive impairment

These assays should not be used to predict the development of dementia or other neurologic conditions or to monitor
 response to therapies.

Specimen Type

CSF

Container

CSF Tube

Collection Instructions

Container/Tube: CSF Sarstedt False bottom Tube-63.614.625( Blue Top Sarstedt tube)
Specimen: 2.5 mL CSF (1.5 mL min)
Transport Temperature: Refrigerated
Patient Preparation: For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins..
Collection Instructions:
1. Perform lumbar puncture and discard the first 1 to 2 mL of cerebrospinal fluid (CSF).
2. Collect CSF directly into one of the listed collection tubes until the tube is at least 50% full*
Note: Polystyrene collection tubes are not acceptable.

Transport Instructions

Refrigerated

Specimen Stability

12 Hours Room Temperature
14 days Refrigerated
60 Days Frozen

Methodology

Electrochemiluminescent Immunoassay (ECLIA)

Days Performed

TAT-2 - 10 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

83520 x 3

PDM

2159233

Result Interpretation

Beta-amyloid (1-42) (Abeta42): >834 pg/mL

Total-Tau: < or =238 pg/mL

Phosphorylated-Tau 181: < or =21.6 pg/mL

p-Tau/Abeta42: < or =0.028

Please Note:   Reference range changes effective May 31, 2023

Forms