Cryoglobulin CRYOGLOB

Synonyms
Allscripts (AEHR) Order Name	Cryoglobulin
Sunrise Clinical Manager (SCM) Order Name	Cryoglobulin, Serum
EPIC Order Name	Cryoglobulin
Clinical Info	Cryoglobulins may be divided into three classes. Type I are monoclonal immunoglobulins and are usually associated with lymphoproliferative disorders. Type II are mixtures of a monoclonal IgM and polyclonal IgG, and are associated with macroglobulinemia and chronic active hepatitis. Type III are mixtures of polyclonal IgM and polyclonal IgG. These are found in a wide variety of disorders. A high percentage of patients with cryoglobulinemia have clinical symptoms, and of these the most common are vascular (ie, purpura and digital necrosis). Raynaud phenomenon is also common. Patients with SLE who are rheumatoid factor-negative but cryoglobulin-positive are more likely to develop renal disease than those who are rheumatoid factor-positive and cryoglobulin-negative.
Specimen Type	Blood
Container	Red Top Tube
Collection Instructions	DO NOT REFRIGERATE Container/Tube: Plain, red-top tube(s), No Serum Separator tubes (SST) Specimen: Send entire tube Transport Temperature: Room Temperature (20 - 26 degrees C) Collection Instructions: Do not centrifuge or refrigerate or freeze.
Transport Instructions	Ambient only (20 - 26 degress C)
Specimen Stability	2 Days Room Temperature Unacceptable Refrigerated or Frozen
Methodology	Visual (Qualitative)
Days Performed	Monday - Sunday Held for 3 - 5 days before reporting
Performing Laboratory	Northwell Health Laboratories
CPT	82585
PDM	5601090
Result Interpretation Negative
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