CD23 CD23

Synonyms

Allscripts (AEHR) Order Name

Not Orderable

Sunrise Clinical Manager (SCM) Order Name

Not Orderable

EPIC Order Name

Clinical Info

Identification of follicular dendritic cells
 
Classification of low-grade B-cell lymphomas
CD23 strongly stains the cytoplasm and membranes of follicular dendritic cells and the membranes of a subset of follicular mantle zone B-lymphocytes. Typically, B-cell small lymphocytic lymphoma/chronic lymphocytic leukemias are CD5 positive and CD23 positive, while mantle cell lymphoma is CD5 positive and CD23 negative. Antibodies to CD23 are diagnostically useful in the classification of low-grade B-cell lymphomas.

Specimen Type

Tissue, Bone Marrow, Body Fluid, CSF, Blood, Swab

Container

Green Top Tube

Collection Instructions

Specimen Type: TECHONLY
Supplies: Immunostain Technical Only Envelope (T693)
Specimen Type: Tissue
Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.
Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block
Specimen Minimum Volume:
Specimen Stability Information:

Specimen Type	Temperature	Time	Special Container
TECHONLY	Ambient (preferred)
	Refrigerated

Transport Instructions

Specimen Stability

Methodology

Immunohistochemistry (IHC)

Days Performed

Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT

88342-TC, primary
88341-TC, if additional IHC

PDM

5200150

Result Interpretation

Forms