Protein S Activity PSACT
Synonyms |
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Allscripts (AEHR) Order Name |
Protein S Free Activity Assay |
Sunrise Clinical Manager (SCM) Order Name |
Protein S Free Activity Assay |
EPIC Order Name |
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Clinical Info |
Confirmation and characterization of protein S (PS) congenital deficiency |
Specimen Type |
Blood |
Container |
Blue Top Tube |
Collection Instructions |
Container/ Tube: Blue-top (sodium citrate) tube Specimen: 1 mL Plasma (minimum 0.5 mL) Centrifuge for 10 minutes and carefully remove 2/3 of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Deliver to a plastic transport tube, cap, and recentrifuge for 10 minutes. Use a second plastic pipette to remove the plasma, staying clear of the platelets at the bottom of the tube. Transfer the plasma into aliquot tube. Transport Temperature: Frozen Stability: 7 Days Frozen Patient Preparation: Avoid warfarin (Coumadin®) therapy for two weeks and heparin therapy for two days prior to the test. Do not draw from an arm with a heparin lock or heparinized catheter. |
Transport Instructions |
Frozen |
Specimen Stability |
7 Days Frozen Patient Preparation: Avoid warfarin (Coumadin®) therapy for two weeks and heparin therapy for two days prior to the test. Do not draw from an arm with a heparin lock or heparinized catheter. |
Methodology |
The patient plasma is added to PS-depleted normal plasma with normal levels of all factors but PS. The mixture is supplemented with excess aPC and factor V is then added. The extent of prolongation of the time to clot formation after calcium chloride is added is proportional to plasma PS activity. |
Days Performed |
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Performing Laboratory |
LabCorp |
CPT |
85306 |
PDM |
5608160 |
Result Interpretation 63-140 % |
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Forms |
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