Warfarin Quant (Coumadin) COUMADIN

Synonyms

Allscripts (AEHR) Order Name

Warfarin Quant (Coumadin)

Sunrise Clinical Manager (SCM) Order Name

Warfarin Quant (Coumadin)

EPIC Order Name

Warfarin Quant (Coumadin)

Clinical Info

Monitoring Levels

Specimen Type

Blood

Container

Lavender-top (EDTA) tube(s)

Collection Instructions

Container/Tube: Lavender Top Tube
Specimen: 1 mL of EDTA plasma (0.2 mL min)
Transport Temperature: Refrigerate
Specimen Preparation: Separate from Cells ADAP or within 2 hours of collection

Alternative Specimen(s) Serum collected in red-top (no gel)

Transport Instructions

Refrigerate

Specimen Stability

30 Days Room Temperature
30 Days Refrigerated
15 Months Frozen

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometr

Days Performed

TAT: 9-12 Days

Performing Laboratory

ARUP
Sent to NMS Labs, Inc.

CPT

80375
LOINC Code; 4098-0

PDM

5913470

Result Interpretation

Reporting Limit: 0.40 mcg/mL

The dosage of warfarin is best adjusted based on the
International Normalized Ratio (INR) for prothrombin
time. Peak plasma concentrations following single
10 mg doses averaged 0.6 mcg/mL for both R-warfarin
and S-warfarin (combined concentration 1.2 mcg/mL).
This test is not chiral specific and does not
distinguish between the R and S enantiomers of
warfarin. The blood to plasma ratio is
approximately 0.5.

Forms