Alkaline P'tase Isoenzymes ALKPISO

Synonyms

Allscripts (AEHR) Order Name

Alkaline Phosphatase Isoenzyme Measure.

Sunrise Clinical Manager (SCM) Order Name

Alkaline Phosphatase Isoenzyme Measure.

EPIC Order Name

Alkaline Phosphatase Isoenzymes

Clinical Info

Evaluate the contribution of the isoforms of ALP from liver, bone, and bowel to total ALP; investigate elevations of ALP to determine the tissue of origin
 

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/ Tube: Gold top tube
Specimen: 1.6 ml Serum (0.8 mL min)
Patient Preparation: Patient should be fasting overnight. Patients who have B or O blood group and are secretors may have an elevated ALP about two hours after a fatty meal.


Note: Overnight fasting is preferred

Transport Instructions

Refrigerated Serum

Specimen Stability

7 Days Room temperature or Refrigerated
3 Months Frozen

Methodology

Electrophoresis
Test Includes: Relative percentages of liver, bone, and intestinal alkaline phosphatase isoenzymes and total alkaline phosphatase

Days Performed

TAT: 4-6 Days

Performing Laboratory

LabCorp

CPT

84075
84080
 
LOINC Code: 24332-9

PDM

5903020

Result Interpretation

LIVER FRACTION
Age (Male)	Percentage Range (Male)
0 to 6 m	Not established
7 m to 5 y	3% to 50%
6 to 17 y	3% to 31%
18 to 100 y	13% to 88%
Age (Female)	Percentage Range (Female)
0 to 6 m	Not established
7 m to 5 y	3% to 51%
6 to 12 y	2% to 25%
13 to 100 y	18% to 85%
BONE FRACTION
Age (Male)	Percentage Range (Male)
0 to 6 m	Not established
7 m to 5 y	48% to 97%
6 to 17 y	67% to 97%
18 to 100 y	12% to 68%
Age (Female)	Percentage Range (Female)
0 to 6 m	Not established
7 m to 5 y	48% to 97%
6 to 12 y	69% to 97%
13 to 100 y	14% to 68%
INTESTINE FRACTION
Age (Male)	Percentage Range (Male)
0 to 30 d	Not established
1 m to 17 y	0% to 8%
18 to 100 y	0% to 18%
Age (Female)	Percentage Range (Female)
0 to 30 d	Not established
1 m to 17 y	0% to 8%
18 to 100 y	0% to 18%

Forms