Tissue Plasminogen Activator TPA

Synonyms

Allscripts (AEHR) Order Name

Tissue Plasminogen Activator Activ Assay

Sunrise Clinical Manager (SCM) Order Name

Tissue Plasminogen Activator Activ Assay

EPIC Order Name

Tissue Plasminogen Activator (tPA) Antigen

Clinical Info

As the primary mediator of endogenous fibrinolysis, elevated tPA levels are strongly associated with an increased risk of arterial vascular disease and have been shown to indicate risk of future myocardial infarction.

Specimen Type

Blood

Container

Blue Top Tube

Collection Instructions

Container/Tube:  Blue-top (3.2% sodium citrate) tube
Specimen: 1mL citrated plasma
Transport Temperature: Frozen
 
Spin down for 10 minutes and carefully remove 2/3 of plasma using a plastic transfer pipette, being careful not to disturb cells and place in a transport tube,
 

Transport Instructions

Frozen

Specimen Stability

Methodology

Tissue plasminogen activator is bound to the wells of a microtiter plate by anti-tPA monoclonal antibodies. Unbound material is washed out of the wells. Bound tPA converts a chromogenic substrate to produce color.

Days Performed

Performing Laboratory

Labcorp-Esoterix

CPT

85415

PDM

5600600

Result Interpretation

< 14.1 ng/mL

Forms