ALPS Screen ALPSSCRN

Synonyms
Allscripts (AEHR) Order Name	ALPS Screen
Sunrise Clinical Manager (SCM) Order Name	Autoimmune Lymphoproliferative Syndrome Screen
EPIC Order Name	Alpha Beta Double-Negative T Cells for Autoimmune Lymphoproliferative Syndrome (Mayo)
Clinical Info	Diagnosing autoimmune lymphoproliferative syndrome, primarily in patients <45 years of age
Specimen Type	Blood
Container	Lavender Top Tube
Collection Instructions	Container/Tube: Lavender (EDTA) Top Tube Specimen: 3 mL whole Blood (0.5 mL min) Transport Temperature: Room Temperature Stability: 72 Hours Room Temperature only
Transport Instructions	Room Temperature
Specimen Stability	72 Hours Room Temperature only
Methodology	Flow Cytometry
Days Performed	TAT: 4 - 7 Days
Performing Laboratory	Mayo Medical Laboratories Specimens are required to be received in the laboratory weekdays and by 4 p.m. Thursday It is recommended that specimens arrive within 24 hours of draw. Samples arriving on the weekend and observed holidays may be canceled.
CPT	86356 x 2 86359
PDM	2059791
Result Interpretation Alpha beta TCR+DNT cells 2-18 years: <2% CD3 T cells 19-70+ years: <3% CD3 T cells Reference values have not been established for patients that are less than 24 months of age. Alpha beta TCR+DNT cells 2-18 years: <35 cells/mcL 19-70+ years: <35 cells/mcL Reference values have not been established for patients that are less than 24 months of age. Alpha beta TCR+DNT B220+ cells 2-18 years: <0.4% CD3 T cells 19-70+ years: <0.3% CD3 T cells Reference values have not been established for patients that are less than 24 months of age. Alpha beta TCR+DNT B220+ cells 2-18 years: <7 cells/mcL 19-70+ years: <6 cells/mcL Reference values have not been established for patients that are less than 24 months of age.
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