N-Methylhistamine, Random Ur NMHR

Synonyms
Allscripts (AEHR) Order Name	N-Methylhistamine, Random Urine
Sunrise Clinical Manager (SCM) Order Name	N-Methylhistamine, Random Urine
EPIC Order Name	Random Urine, N-Methylhistamine
Clinical Info	Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis
Specimen Type
Specimen Volume
Container	Urine Cup
Collection Instructions	Specimen Type: Urine Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as these medications increase N-methylhistamine (NMH) levels. Supplies: Aliquot Tube, 5 mL (T465) Container/Tube: Plastic vial, 5-mL Specimen Volume: 5 mL Collection Instructions: 1. Collect a random urine specimen within a few hours of symptom onset. 2. No preservative. Specimen Minimum Volume: 3 mL Specimen Stability Information: Refrigerated (preferred) 28 days / Frozen 28 days / Ambient 14 days
Transport Instructions
Specimen Stability
Methodology	NMHR1: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) CRETR: Enzymatic Colorimetric Assay
Days Performed	Tuesday, Thursday
Performing Laboratories	Mayo Clinic Laboratories in Rochester
CPT	82542 82570
PDM	2059266
Result Interpretation N-METHYLHISTAMINE 0-5 years: 120-510 mcg/g creatinine 6-16 years: 70-330 mcg/g creatinine >16 years: 30-200 mcg/g creatinine CREATININE Males: 930-2955 mg/24 hours Females: 603-1783 mg/24 hours Reference values have not been established for patients who are less than 18 years of age
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