Comprehensive Celiac Cascade CDCOM

Synonyms

Allscripts (AEHR) Order Name

Comprehensive Celiac Cascade

Sunrise Clinical Manager (SCM) Order Name

Comprehensive Celiac Cascade

EPIC Order Name

Celiac Disease Comprehensive Cascade

Clinical Info

Evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease)
 

Specimen Type

Container

Yellow Top Tube

Collection Instructions

Specimen Type: Serum Whole Blood ACD-B
Both blood and serum are required.
 
Specimen Type: Blood
Container/Tube: Yellow top (ACD [solution B])
Specimen Volume: 6 mL
Collection Instructions: Do not transfer blood to other containers.
 
Specimen Type: Serum
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 2 mL
Specimen Minimum Volume: Blood: 3 mL Serum: 1.5 mL
Specimen Stability Information:
Specimen TypeTemperatureTimeSpecial Container
SerumRefrigerated (preferred)14 days
 Frozen 21 days
Whole Blood ACD-BRefrigerated(preferred)
 Ambient 

Transport Instructions

Specimen Stability

Methodology

IGA: Nephelometry
CELI2: Polymerase Chain Reaction (PCR)/Sequence-Specific Oligonucleotide Probe (SSO)

Days Performed

IgA, tTG IgA, Gliadin IgA, tTG IgG, Gliadin IgG: Monday through Saturday
HLA-DQ Typing, EMA: Monday through Friday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT

82784
81376 x 2
83516-Deamidated gliadin IgA (if appropriate)
83516-Deamidated gliadin IgG (if appropriate)
83516-tTG IgA (if appropriate)
83516-tTG IgG (if appropriate)
86255-Endomysial antibodies (if appropriate)

PDM

1859701

Result Interpretation

IMMUNOGLOBULIN A (IgA)
0-<5 months: 7-37 mg/dL
5-<9 months: 16-50 mg/dL
9-<15 months: 27-66 mg/dL
15-<24 months: 36-79 mg/dL
2-<4 years: 27-246 mg/dL
4-<7 years: 29-256 mg/dL
7-<10 years: 34-274 mg/dL
10-<13 years: 42-295 mg/dL
13-<16 years: 52-319 mg/dL
16-<18 years: 60-337 mg/dL
?18 years: 61-356 mg/dL
 
HLA-DQ TYPING
Presence of DQ2 or DQ8 alleles associated with celiac disease

Forms

edit