Renal Cell Cancer Panel Ren Cancer

Synonyms

Allscripts (AEHR) Order Name

Not Orderable

Sunrise Clinical Manager (SCM) Order Name

Not Orderable

EPIC Order Name

Renal Cancer Panel

Clinical Info

This test is appropriate for patients to verify the genetic basis of cancer in families indicative or suggestive of a predisposition to renal cancer. VHL, MET, FLCN, FH, TSC1 and TSC2 are the genes that are the most often associated with classic forms of hereditary renal cancer, there are several other genes that cause an increased risk of renal cancer. For example, if the family history consists of multiple types of cancer, such as renal cancer in addition to pancreatic cancer, this may be associated with a cancer syndrome such as VHL or Lynch syndrome. Results may help in determining treatment and management, as well as identification of at-risk family members.

Specimen Type

Blood, Other

Specimen Volume

2 - 5 mL Whole Blood

Container

Lavender Top Tube or Buccal (Oral Cheek Swab)

Collection Instructions

Container/Tube:  Lavender top tube
Specimen:  2 - 5 mL Whole Blood
 
Note:   Test requires indication for testing and family history submitted  with specimen

Transport Instructions

Room Temperature

Specimen Stability

Methodology

Genotyping by Next Generation Sequencing
 
Genes:
 BAP1, EPCAM, FH, FLCN, MET, MITF, MLH1, MSH2, MSH6, PMS2, PTEN, SDHB, SDHC, SDHD, TP53, TSC1, TSC2, VHL

Days Performed

TAT:  21-29 Days

Performing Laboratory

GeneDx

CPT

81435

PDM

1659884

Result Interpretation

Forms

• Hereditary Cancer Testing Requisition