Mitochondrial Fatty Acids (C8-C18) FAPM

Synonyms

Allscripts (AEHR) Order Name

MITOCHOND FATTY ACIDS (C8-C18)

Sunrise Clinical Manager (SCM) Order Name

Mitochondrial Fatty AcIds (C8-C18)

EPIC Order Name

Fatty Acid Profile, Mitochondrial (C8-C18)

Clinical Info

Biochemical diagnosis of inborn errors of mitochondrial fatty acid oxidation, including deficiencies of medium-chain acyl-Co-A dehydrogenase, long-chain 3-hydroxyacyl-Co-A dehydrogenase, very long-chain acyl-Co-A dehydrogenase, and glutaric acidemia type 2

Specimen Type

Blood

Specimen Volume

Container

Gold Top Tube

Collection Instructions

Specimen Type: Serum
Patient Preparation:
1. For nutritional assessment, patient should fast overnight (12-14 hours); for patients with a suspected fatty acid oxidation disorder, collect prior to next feeding as fasting is contraindicated.
2. Patient must not consume any alcohol for 24 hours before the specimen is collected.
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Specimen Minimum Volume: 0.15 mL
Specimen Stability Information:
Specimen TypeTemperatureTimeSpecial Container
SerumFrozen (preferred)92 days
 Refrigerated 72 hours

Transport Instructions

Specimen Stability

Methodology

Gas Chromatography-Mass Spectrometry (GC-MS) Stable Isotope Dilution

Days Performed

Monday through Friday

Performing Laboratories

Mayo Clinic Laboratories in Rochester

CPT

82725

PDM

5901456

Result Interpretation

Octanoic Acid, C8:0
<1 year: 7-63 nmol/mL
1-17 years: 9-41 nmol/mL
?18 years: 8-47 nmol/mL
 
Decenoic Acid, C10:1
<1 year: 0.8-4.8 nmol/mL
1-17 years: 1.6-6.6 nmol/mL
?18 years: 1.8-5.0 nmol/mL
 
Decanoic Acid, C10:0
<1 year: 2-62 nmol/mL
1-17 years: 3-25 nmol/mL
?18 years: 2-18 nmol/mL
 
Lauroleic Acid, C12:1
<1 year: 0.6-4.8 nmol/mL
1-17 years: 1.3-5.8 nmol/mL
?18 years: 1.4-6.6 nmol/mL
 
Lauric Acid, C12:0
<1 year: 6-190 nmol/mL
1-17 years: 5-80 nmol/mL
?18 years: 6-90 nmol/mL
 
Tetradecadienoic Acid, C14:2
<1 year: 0.3-6.5 nmol/mL
1-17 years: 0.2-5.8 nmol/mL
?18 years: 0.8-5.0 nmol/mL
 
Myristoleic Acid, C14:1
<1 year: 1-46 nmol/mL
1-17 years: 1-31 nmol/mL
?18 years: 3-64 nmol/mL
 
Myristic Acid, C14:0
<1 year: 30-320 nmol/mL
1-17 years: 40-290 nmol/mL
?18 years: 30-450 nmol/mL
 
Hexadecadienoic Acid, C16:2
<1 year: 4-27 nmol/mL
1-17 years: 3-29 nmol/mL
?18 years: 10-48 nmol/mL
 
Palmitoleic Acid, C16:1w7
<1 year: 20-1,020 nmol/mL
1-17 years: 100-670 nmol/mL
?18 years: 110-1,130 nmol/mL
 
Palmitic Acid, C16:0
<1 year: 720-3,120 nmol/mL
1-17 years: 960-3,460 nmol/mL
?18 years: 1,480-3,730 nmol/mL
 
Linoleic Acid, C18:2w6
?31 days: 350-2,660 nmol/mL
32 days-11 months: 1,000-3,300 nmol/mL
1-17 years: 1,600-3,500 nmol/mL
?18 years: 2,270-3,850 nmol/mL
 
Oleic Acid, C18:1w9
<1 year: 250-3,500 nmol/mL
1-17 years: 350-3,500 nmol/mL
?18 years: 650-3,500 nmol/mL
 
Stearic Acid, C18:0
<1 year: 270-1,140 nmol/mL
1-17 years: 280-1,170 nmol/mL
?18 years: 590-1,170 nmol/mL

Forms

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