Synonyms
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Liver Fibrosis, Fibro Test
ActiTest
Fibro Test
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Allscripts (AEHR) Order Name
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HEPATITIS C VIRUS (HCV) FIBROSURE
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Sunrise Clinical Manager (SCM) Order Name
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Hepatitis C Virus Fibrosure
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EPIC Order Name
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Hepatitis C Virus (HCV) FibroSure (LabCorp)
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Clinical Info
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For the assessment of liver status following a diagnosis of HCV as well as post-treatment assessment of liver status six months after completion of antiviral therapy. For use in patients who are at risk of complications from a liver biopsy.
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Specimen Type
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Blood
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Container
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Gold Top Tube
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Collection Instructions
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Container/Tube: 2 Gold top tube- serum gel top
Specimen: 3.5 mL serum (2 mL min) - Separate serum from cells within two hours of collection.
Transport Temperature: Frozen
Stability: 72 Hours Room Temperature or Refrigerated
7 Days Frozen
Patient should be fasting for at least eight hours.
Note: Please submit Two aliquots: 2.5 ml frozen serum in one & 0.5 ml in other tube ( minimum volume: 1.5 mL Frozen serum + 0.5 mL Frozen serum)
Patient Preparation Patient should be fasting for at least eight hours
Causes for Rejection Gross hemolysis; gross lipemia; improper labeling; nonfasting specimen; patient less than 14 years of age
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Transport Instructions
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Frozen
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Specimen Stability
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72 Hours Room Temperature or Refrigerated
7 Days Frozen
Patient should be fasting for at least eight hours.
Note: Please submit Two aliquots: 2.5 ml frozen serum in one & 0.5 ml in other tube ( minimum volume: 1.5 mL
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Methodology
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FibroSURE
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Days Performed
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Monday - Friday, 7 Day TAT
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Performing Laboratory
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LabCorp of America
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CPT
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81596
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PDM
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5907810
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Result Interpretation
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Individual Serum Markers
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Male
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Female
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Alanine aminotransferase (ALT)
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0−55 IU/L
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0−40 IU/L
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α2-Macroglobulin
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110−276 mg/dL
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110−276 mg/dL
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Apolipoprotein A-1
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110−180 mg/dL
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110−205 mg/dL
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Bilirubin, total
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0.0−1.2 mg/dL
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0.0−1.2 mg/dL
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γ-Glutamyl transferase (GGT)
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0−65 IU/L
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0−60 IU/L
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Haptoglobin
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34−200 mg/dL
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34−200 mg/dL
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METAVIR Group Scoring System
Fibrosis Stage (FibroTest)
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Range
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F0−No fibrosis
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0.00−0.21
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F0−F1
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0.21−0.27
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F1−Portal fibrosis
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0.27−0.31
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F1−F2
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0.31−0.48
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F2−Bridging fibrosis with few septa
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0.48−0.58
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F3−Bridging fibrosis with many septa
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0.58−0.72
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F3−F4
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0.72−0.74
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F4−Cirrhosis
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0.74−1.00
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Activity Stage (ActiTest)
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Range
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A0−No activity
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0.00−0.17
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A0−A1
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0.17−0.29
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A1−Minimal activity
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0.29−0.36
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A1−A2
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0.36−0.52
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A2−Moderate activity
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0.52−0.60
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A2−A3
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0.60−0.63
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A3−Severe activity
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0.63−1.00
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Forms
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