Beta-2 Transferrin B2TRANS

Synonyms

Allscripts (AEHR) Order Name

Beta-2 Transferrin

Sunrise Clinical Manager (SCM) Order Name

Beta-2 Transferrin, Body Fluid

EPIC Order Name

Beta-2 Transferrin: Detection of CSF in Other Body Fluids

Clinical Info

Determining the presence of cerebrospinal fluid in body fluids
The diagnosis of cerebrospinal fluid (CSF) rhinorrhea or otorrhea (leakage of CSF into the nose or ear canal, usually as a result of head trauma, tumor, congenital malformation, or surgery) is often difficult to confirm. Traditional chemical analyses (eg, glucose, protein, specific gravity) are unreliable. Radiographic studies, especially those involving the injection of dyes or radiographic compounds, are costly and may introduce additional risks to the patient. Prompt diagnosis and localization facilitates appropriate decisions and decreases the risk of meningitis.

Beta-trace protein (prostaglandin D synthase) is one of the most abundant proteins in CSF and has a very low concentration in other body fluids. Elevated concentrations of beta-trace protein in body fluid or drainage are consistent with CSF leakage.

Specimen Type

Body Fluid

Container

Sterile

Collection Instructions

Container/Tube: Sterile Container
Specimen: 1mL Body fluid (0.5 m) Indicate on the sample
Transport Temperature: Refrigerated

Transport Instructions

Specimen Stability

14 Days Room Temperature
14 days Refrigerated
30 days Frozen

Methodology

Nephelomtry

Days Performed

TAT: 2-4 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

86335
LOINC Code: 57733-8

PDM

5950915

Result Interpretation

Negative, no beta-2 transferrin (spinal fluid) detected

Forms