SHIGA TOXIN SHIGA TOXIN

Synonyms

Allscripts (AEHR) Order Name

E.Coli Shiga Toxin

Sunrise Clinical Manager (SCM) Order Name

Shiga Toxin

EPIC Order Name

Shiga Toxin, Stool

Clinical Info

Detect the presence of Shiga-toxin-producing enterohemorrhagic E coli
 

Specimen Type

Stool

Container

Stool Container

Collection Instructions

Container/Tube: Stool culture transport vial; culture collection swab may be used to collect rectal swabs or a swab of fecal material, then swab should be placed in stool culture transport vial (Carey-Blair C/S media).
Specimen:  1-2 g placed in stool transport vial  ( Rectal swab with obvious stool -min)
Transport Temperature:   Room Temperature
 
Causes for Rejection Specimen received in grossly leaking transport container; diapers; dry specimen; specimen submitted in fixative or additive; specimen received in expired transport media or incorrect transport device; inappropriate specimen transport conditions (not in a C&S vial or in an overfilled C&S vial); specimen received after prolonged delay in transport (usually more than 72 hours); specimen stored or transported frozen; wooden shaft swab in transport device; unlabeled specimen or name discrepancy between specimen and request label
 

Transport Instructions

Room Temperature

Specimen Stability

Methodology

Detection of enterohemorrhagic E coli Shiga toxins by enzyme immunoassay (EIA)

Days Performed

Limitations There are four types of pathogenic E coli (see table). This test detects only enterohemorrhagic E coli; tests are not available for the other pathogenic E coli.
Four Major Categories of Diarrheagenic E coli
Category
Clinic Manifestation
Enterotoxigenic (ETEC)
Travelers' diarrhea and infant diarrhea in less developed countries
Enteropathogenic (EPEC)
Infant diarrhea
Enterohemorrhagic (EHEC)
Hemorrhagic colitis
Hemolytic uremic syndrome
Thrombotic thrombocytopenia purpura
Enteroinvasive (EIEC)
Dysentery

Performing Laboratory

LabCorp of America

CPT

87427
 
LONIC code: 21262-1

PDM

6400035

Result Interpretation

No enterohemorrhagic E coli Shiga toxin detected
 
There are four types of pathogenic E coli (see table). This test detects only enterohemorrhagic E coli; tests are not available for the other pathogenic E coli.
 
Four Major Categories of Diarrheagenic E coli

Category	Clinic Manifestation
Enterotoxigenic (ETEC)	Travelers' diarrhea and infant diarrhea in less developed countries
Enteropathogenic (EPEC)	Infant diarrhea
Enterohemorrhagic (EHEC)	Hemorrhagic colitis Hemolytic uremic syndrome Thrombotic thrombocytopenia purpura
Enteroinvasive (EIEC)	Dysentery

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