HLX WM/LPL Case HLX WM/LPL Case

Synonyms	MYD88 L265P CXCR4
Allscripts (AEHR) Order Name	MYD88 and CXCR4 Panel Mutation Analysis
Sunrise Clinical Manager (SCM) Order Name	MYD88 and CXCR4 Panel Mutation Analysis
EPIC Order Name	MYD88 and CXCR4 Panel Molecular Detection
Clinical Info	Detection of MYD88 L265P mutation is useful in differentiating LPL from other B-cell lymphoproliferative disorders with overlapping clinicopathological features. CXCR4 mutations are associated with resistance to ibrutinib in patients with Waldenstrom macroglobulinemia (WM).
Specimen Type	Blood, Bone Marrow
Specimen Volume	1- 3 mL Whole Blood or Bone Marrow
Container	Lavender Top Tube
Collection Instructions	Container/Tube; Lavender top Tube Specimen: 1 - 3 mL Whole Blood or Bone Marrow
Transport Instructions	Room Temperature
Specimen Stability	Specimens are stable for a week refrigerated
Methodology	Allele specific Real Time PCR
Days Performed	Monday through Friday TAT: 8 Calendar days
Performing Laboratory	Northwell Health Laboratories
CPT	81479 and 81305
PDM	248468
Result Interpretation Detected (mutation is present) Not detected (mutation is absent)
Forms	Molecular test Requisition Form Heme/Onc Requisition

Synonyms