Enhanced Liver Fibrosis (ELF) ELF

Synonyms

Allscripts (AEHR) Order Name

Enhanced Liver Fibrosis (ELF)

Sunrise Clinical Manager (SCM) Order Name

Enhanced Liver Fibrosis (ELF)

EPIC Order Name

Enhanced Liver Fibrosis (ELF)

Clinical Info

 Non-invasive test that provides a simple, unitless numeric score that is generated via an algorithm for use in advanced liver fibrosis. It is indicated as a prognostic marker in conjunction with other laboratory findings and clinical assessments in patients with advanced fibrosis (F3 or F4) due to nonalcoholic steatohepatitis (NASH), now called metabolic dysfunction-associated steatohepatitis (MASH), to assess the likelihood of progression to cirrhosis and liver-related clinical events

Specimen Type

Blood

Specimen Volume

2.5 mL serum ( 1mL min)

Container

Gold Top Tube or Red Top Tube

Collection Instructions

Specimen: 2.5 mL serum (1mL min) 
Separate serum fron cells within 2 hours of collection.

Transport Instructions

Refrigerated

Specimen Stability

2 Days Room Temperature
7 Days Refrigerated
Up to 12 Month Frozen at <=20 C

Methodology

Direct chemiluminometric

Days Performed

TAT: 4-7 Days

Performing Laboratory

LabCorp

CPT

81517
LOINC Code: 88055-9

PDM

245342

Result Interpretation

ELF™ Score Interpretation:

Risk cut-offs to assess the likelihood of progression to cirrhosis and liver-related clinical events within 3.9 years following baseline ELF score (IQR: 14.0-22.4 months):5

Lower risk

<9.80

Mid risk

9.80–11.29

Higher risk

>11.29

Note: The ELF™ Score is a unitless numerical value.

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