Reverse Triiodothyronine (rT3)

Synonyms

  • LAB138
  • T3, REVERSE
  • T3R
  • TRI-IODOTHYRONINE
  • TRIIODOTHYRONINE, REVERSE (T3REV)

Cerner Name

Triiodothyronine Reverse

Clinical Info

Reverse triiodothyronine (rT3) is an isomer of triiodothyronine (T3) with no demonstrated biological activity.1,2 The majority of rT3 is produced through peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus of thyroxine (T4). A lesser amount of rT3 is secreted directly by the thyroid gland. Reverse T3 is biologically inactive and does not stimulate thyroid hormone receptors.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1.2 mL serum (0.8 mL min)

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold Top Tube(s)
Specimen: 1.2 mL serum (0.8 mL min)
Transport Temperature: Refrigerate

Transport Instructions

Refrigerate

Specimen Stability

Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Days Performed

Tuesday - Saturday
 
TAT 2 - 3 Days

Performing Laboratories

LabCorp Burlington

CPT

84482
 
LOINC - 3052-8

PDM

5902690

Results
Component Name Base Name Common Name External Name
TRIIODOTHYRONINE, REVERSE TRIIODOTH TRIIODOTHYONINE, REVERSE Triiodothyronine, Reverse

Result Interpretation

 

Age Range (ng/dL)
Premature (26 to 31 wk) 33.0−147.0
Premature (32 to 35 wk) 49.0−217.0
Full-term (2 to 7 d) 33.0−206.0
8 d to 5 m 13.0−107.0
6 to 12 m 8.1−52.8
1 to 15 y 8.3−22.9
16 y and older 9.2−24.1

 

Forms
Endocrine LAB138 build edit