Clonazepam Level

Synonyms

  • CLONAPAM
  • CLONAZEPAM LEVEL
  • KLONOPIN
  • LAB466
  • RIVOTRIL

Cerner Name

Clonapin (Clonazepam)

Clinical Info

Evaluate toxicity; monitor therapeutic levels
Information
The drug is used in the treatment of petit mal variant (Lennox-Gastaut), akinetic seizures and myoclonic seizures. Serum peak levels occur approximately two hours after oral administration.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

4 mL serum (1.1 mL min)

Container

Red Top Tube

Collection Instructions

Container/Tube:  Plain, red-top tube - Serum gel tube is not acceptable.
Specimen:  4 mL serum (1.1 mL min)
Transport Temperature:  Refrigerated
Stability: 14 Days Room Temperature, Refirgerated or Frozen
 

Transport Instructions

Refrigerated

Specimen Stability

14 Days Room Temperature, Refirgerated or Frozen
 

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Days Performed

Daily
TAT: 3 - 5 Days

Performing Laboratories

LabCorp

CPT

80346
 
LONIC: 3494-2

PDM

5900457

Results
Component Name Base Name Common Name External Name
CLONAPIN, SERUM CLONAPIN CLONAPIN, SERUM Clonazepam (Klonopin)
CLONAPIN 7-AMINO CLONAPIN CLONAPIN 7 AMINO Clonapin 7-Amino

Result Interpretation

Therapeutic:  20 - 70 ng/mL
Potentially Toxix: > 80 ng/mL
 
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
 

Forms
Tox/TDM LAB466 build edit