Streptococcus pneumoniae Antibody Serotyping

Synonyms

  • LAB778
  • PNEUMOCOCCAL IGG SEROTYPES
  • Pneumovax
  • Prevnar
  • S. PNEUMONIAE
  • STREP PNEUMONIAE ANTIBODY SEROTYPES
  • STREPTOCOCCUS PNEUMONIAE IGG ANTIBODY

Cerner Name

Pneumococcal IgG Serotypes

Clinical Info

Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent vaccines
Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 
20-valent pneumococcal vaccines
Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as 
part of an evaluation for humoral or combined immunodeficiencies

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

0.5 mL serum (0.4 mL min)

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold Top Tube
Volume: 0.5 mL (0.4 mL min)
Transport Temperature: Refrigerated

Transport Instructions

Refrigerated

Specimen Stability

21 Days Refrigerated or Frozen

Methodology

Bead-Based Multiplex Immunoassay

Days Performed

Monday through Friday

Performing Laboratories

Mayo Medical Laboratories

CPT

86581

PDM

5905600

Results
Component Name Base Name Common Name External Name
S PNEUMONIAE IGG SEROTYPE 1 PNEUIGGST S PNEUMONIAE IGG SEROTYPE 1 S Pneumoniae IgG Serotype 1
STREPTOCOCCUS PNEUMONIAE SEROTYPE 33F STRPNESER33F STREP PNEUMONIAE SERO 33F S Pneumoniae IgG Serotype 33F
STREPTOCOCCUS PNEUMONIAE SEROTYPE 9V STRPNESER9V STREP PNEUMONIAE SERO 9V S Pneumoniae IgG Serotype 9V
STREPTOCOCCUS PNEUMONIAE SEROTYPE 19A STRPNESER19A STREP PNEUMONIAE SERO 19A S Pneumoniae IgG Serotype 19A
S PNEUMONIAE IGG SEROTYPE 18C PNEUIGGST S PNEUMONIAE IGG SEROTYPE 18C S Pneumoniae IgG Serotype 18C
STREPTOCOCCUS PNEUMONIAE SEROTYPE 15B STRPNESER15B STREP PNEUMONIAE SERO 15B S Pneumoniae IgG Serotype 15B
STREPTOCOCCUS PNEUMONIAE SEROTYPE 7F STRPNESER7F STREP PNEUMONIAE SERO 7F S Pneumoniae IgG Serotype 7F
STREPTOCOCCUS PNEUMONIAE SEROTYPE 11A STRPNESER11A STREP PNEUMONIAE SERO 11A S Pneumoniae IgG Serotype 11A
STREPTOCOCCUS PNEUMONIAE SEROTYPE 10A STRPNESER10A STREP PNEUMONIAE SERO 10A S Pneumoniae IgG Serotype 10A
STREPTOCOCCUS PNEUMONIAE SEROTYPE 6B STRPNESER6B STREP PNEUMONIAE SERO 6B S Pneumoniae IgG Serotype 6B
STREPTOCOCCUS PNEUMONIAE SEROTYPE 23F STRPNESER23F STREP PNEUMONIAE SERO 23F S Pneumoniae IgG Serotype 23F
STREPTOCOCCUS PNEUMONIAE SEROTYPE 22F STRPNESER22F STREP PNEUMONIAE SERO 22F S Pneumoniae IgG Serotype 22F
STREPTOCOCCUS PNEUMONIAE SEROTYPE 20 STRPNESER20 STREP PNEUMONIAE SERO 20 S Pneumoniae IgG Serotype 20
STREPTOCOCCUS PNEUMONIAE SEROTYPE 19F STRPNESER19F STREP PNEUMONIAE SERO 19F S Pneumoniae IgG Serotype 19F
STREPTOCOCCUS PNEUMONIAE SEROTYPE 17F STRPNESER17F STREP PNEUMONIAE SERO 17F S Pneumoniae IgG Serotype 17F
STREPTOCOCCUS PNEUMONIAE SEROTYPE 14 STRPNESER14 STREP PNEUMONIAE SERO 14 S Pneumoniae IgG Serotype 14
STREPTOCOCCUS PNEUMONIAE SEROTYPE 12F STRPNESER12F STREP PNEUMONIAE SERO 12F S Pneumoniae IgG Serotype 12F
STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 STRPNESER8 STREP PNEUMONIAE SERO 8 S Pneumoniae IgG Serotype 8
STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 STRPNESER4 STREP PNEUMONIAE SERO 4 S Pneumoniae IgG Serotype 4
STREPTOCOCCUS PNEUMONIAE SEROTYPE 3 STRPNESER3 STREP PNEUMONIAE SERO 3 S Pneumoniae IgG Serotype 3
STREPTOCOCCUS PNEUMONIAE SEROTYPE 2 STRPNESER2 STREP PNEUMONIAE SERO 2 S Pneumoniae IgG Serotype 2
STREPTOCOCCUS PNEUMONIAE SEROTYPE 5 STRPNESER5 STREP PNEUMONIAE SERO 5 S Pneumoniae IgG Serotype 5
STREPTOCOCCUS PNEUMONIAE SEROTYPE 9N STRPNESER9N STREP PNEUMONIAE SERO 9N S Pneumoniae IgG Serotype 9N
PNEUMSINTERP PNEUMSINTERP PNEUMSINTERP S Pneumoniae IgG Serotype Interpretation

Result Interpretation

Results are reported in mcg/mL. 

  Effective : August 3, 2023

Serotype

Normal value

1 (1)

 > or =1.0

2 (2)

 > or =1.0

3 (3)

 > or =1.0

4 (4)

 > or =1.0

5 (5)

 > or =1.0

8 (8)

 > or =1.0

9N (9)

 > or =1.0

12F (12)

 > or =1.0

14 (14)

 > or =1.0

17F (17)

 > or =1.0

19F (19)

 > or =1.0

20 (20)

 > or =1.0

22F (22)

 > or =1.0

23F (23)

 > or =1.0

6B (26)

 > or =1.0

10A (34)

 > or =1.0

11A (43)

 > or =1.0

7F (51)

 > or =1.0

15B (54)

 > or =1.0

18C (56)

 > or =1.0

19A (57)

 > or =1.0

9V (68)

 > or =1.0

33F (70)

 > or =1.0
INTERPRETATION 
 

As a general guideline, nonimmunocompromised adults develop IgG antibodies approximately 4 to 6 weeks following nonconjugated vaccination.

 

Either of the following conditions is consistent with a normal response to Streptococcus pneumonia vaccination:

1. When comparing pre- and post-vaccination samples, antibody concentrations increased by at least 2-fold for

a. >50% of serotypes in children <6 years of age

b. >70% of serotypes for individuals >6 years of age

 

2. In either a pre- or post-vaccination sample, antibody concentrations >/= 1.0 mcg/mL for

a. >50% of serotypes for children <6 years of age

b. >70% of serotypes for individuals >6 years of age

Forms
ID Sendouts LAB778 build edit