Imipramine Level

Synonyms

  • DRUG
  • IMIPRAMINE LEVEL
  • LAB684
  • TOFRANIL

Cerner Name

Imipramine and Desipramine, Serum

Clinical Info

Monitoring serum concentration during therapy
Evaluating potential toxicity
The test may also be useful to evaluate patient compliance

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 mL (0.5 mL min)

Container

Red Top Tube

Collection Instructions

Container/Tube: Red top tube
Specimen : 1 mL (0.5 mL min)
Collection Instructions:
1. Draw specimen immediately before next scheduled dose
(minimum 12 hours after last dose).
2. Serum must be
separated from cells within 2 hours of draw.
Transport Temperature: Refrigerated
Stability: 7 Days Room Temperature
28 Days Refrigerated or Frozen

Transport Instructions

Refrigerated

Specimen Stability

7 Days Room Temperature
28 Days Refrigerated or Frozen

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

Monday through Friday; Varies

Performing Laboratories

Mayo Medical Laboratories

CPT

80335
G0480 (if appropriate)
LOINC Code: 42123-9

PDM

5915021

Results
Component Name Base Name Common Name External Name
IMIPRAMINE QUANTITATIVE IMIPRAMINE IMIPRAMINE QUANTITATIVE Imipramine Quantitative
DESIPRAMINE QUANTITATIVE DESIPRAMINEQ DESIPRAMINE QUANTITATIVE Desipramine Quantitative
IMIPRAMINE/DESIPRAMINE TOTAL ESIP IMIPRAMINE DESIPRAMINE TOTAL Imipramine and Desipramine

Result Interpretation

IMIPRAMINE AND DESIPRAMINE

Total therapeutic concentration: 175-300 ng/mL

 

DESIPRAMINE ONLY

Therapeutic concentration: 100-300 ng/mL

Note: Therapeutic ranges are for specimens drawn at
trough (ie, immediately before

Forms
Tox/TDM LAB684 build edit