Amitriptyline Level

Synonyms

  • Amitril
  • Amitriptyline & Metabolite
  • AMITRIPTYLINE LEVEL
  • ELAVIL
  • Endep
  • Etrafon
  • LAB681
  • Limbitrol
  • Triavil

Cerner Name

Amitriptyline, Quantitative

Clinical Info

The tricyclics are used to treat depression. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

3mL of serum ( 1.5 mL min)

Container

Red Top Tube

Collection Instructions

Container/Tube:  Plain, red-top tube(s)
Specimen:  3mL of serum ( 1.5 mL min)
Transport Temperature:  Refrigerate
 
Instructions:  Collect at stady-state trough concentration. Specimen should be collect 12 hours after dose.

Transport Instructions

Refrigerate

Specimen Stability

Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
 
Includes: Amitriptyline, Nortriptyline and Total

Days Performed

Monday through Friday

Performing Laboratories

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

CPT

80152

PDM

5915001

Results
Component Name Base Name Common Name External Name
AMITRIPTYLINE, QUANTITATIVE AMITRIPQNT AMITRIPTYLINE, QUANTITATIVE Amitriptyline, Quantitative
NORTRIPTYLINE QUANTITATIVE NORTRIPT NORTRIPTYLINE QUANTITATIVE Nortriptyline Quantitative
AMITRIP/NORTRIPTYLINE TOTAL AMITNORTTOT AMITRIP NORTRIPTYLINE TOTAL Amitrip/Nortriptyline Total
AMITRIP/NORTRIPYLINE NOTE AMITNORTNOTE AMITRIP NORTRIPTYLINE NOTE Amitrip/Nortriptyline Note

Result Interpretation

Total  100- 250 mcg/L

Forms
Tox/TDM LAB681 build edit