Lipoprotein (a)

Synonyms

  • LAB563
  • LIPOPROTEIN A (LPA)
  • LIPOPROTEIN A, SERUM
  • LP(A)
  • LP(A) APOPROTEIN
  • LPA

Cerner Name

Lipoprotein (a)

Clinical Info

Lp(a) is an independent prospective risk factor for coronary heart disease. Lp(a) determination is intended for use in conjunction with clinical evaluation, patient risk assessment, and other lipid tests to evaluate disorders of lipid metabolism and to assess coronary heart disease in specific populations.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 mL of serum ( 0.5 mL min)

Container

Gold Top Tube

Collection Instructions

Separate serum from cells as soon as possible (within two hours).

Transport Instructions

Refrigerate

Specimen Stability

5 days at 15-25 °C
20 days at 2-8 °C
13 weeks frozen at -20 °C (± 5 °C)

Methodology

Immunoturbidimetric

Days Performed

Monday to Sunday

Performing Laboratories

Northwell Health Core Lab (CFAM)

CPT

83695

PDM

5904270

Results
Component Name Base Name Common Name External Name
LIPOPROTEIN (A) LIPOA LIPOPROTEIN A Lipoprotein (a)

Result Interpretation

< 75 nmol/L = Low Lp(a) attributable ASCVD risk

75 nmol/L to 125 nmol/L = Intermediate Lp(a) attributable ASCVD risk

>= 125 nmol/L = High Lp(a) attributable ASCVD risk, with increasing risk with higher Lp(a) values


Elevated Lp(a) is an important risk factor for atherosclerotic CVD and calcific aortic valve disease. Lp(a) levels represent a continuum of risk, not a risk threshold at a dichotomous cutpoint.

Reference:

National Lipid Association (NLA) scientific statement on use of lipoprotein(a) in clinical practice (Journal of Clinical Lipidology, 2024; 18, e308-e319)

Forms
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Workgroup: Chemistry
Procedure Master Number: LAB563
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