VWF Multimers

Synonyms

  • FACTOR 8
  • FACTOR VIII
  • LAB1111
  • MULTIMERS
  • VWF
  • VWF MULTIMERS

Cerner Name

VWF Multimer

Clinical Info

This test is used to measure the relative levels of von Willebrand low molecular weight multimers (LMWM), intermediate molecular weight multimers (IMWM) and high molecular weight multimers (HMWM) in plasma.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

2.0 mL citrated plasma (Min Volume 1.0 mL)

Container

Blue Top Tube

Collection Instructions

Container/Tube: Light blue-top (3.2% sodium citrate) tube
Specimen: 2.0 mL citrated plasma (Min 1.0 mL)
Transport Temperature: Frozen
Collection Instructions:
Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.24 Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.25,26 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples unless the sample is collected using a winged (butterfly) collection system. With a winged blood collection set, a discard tube should be drawn first to account for the dead space of the tubing and prevent under-filling of the evacuated tube.27,28 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternative anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes.

Transport Instructions

Frozen

Specimen Stability

Freeze; four freeze/thaw cycles are acceptable. Stable refrigerated for four hours.

Methodology

Days Performed

TAT: 6-8 Days

Performing Laboratories

  • NWH CL Send Outs-Labcorp

CPT

85247

PDM

5600318

Results

Component Name Base Name Common Name External Name
VON WILLEBRAND FACTOR MULTIMER ASSAY VWFMULT VON WILLEBRAND FACTOR MULTIMER ASSAY VWF Multimers

Result Interpretation


This test includes von Willebrand factor activity (VWF:Ag); von Willebrand factor antigen (VWF:Ac); VWF:Ag/ VWF:Ac ratio; and von Willebrand Multimer results including percent Intermediate and High Molecular Weight Fractions.

Forms

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Workgroup: Hematology
Procedure Master Number: LAB1111
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