Acylcarnitine Profile, Quantitative, Plasma

Synonyms

  • ACYL CARNITINE, PLASMA
  • ACYLCARNITINES, PLASMA, QUANTITATIVE
  • LAB429

Cerner Name

Acylcarnitine, Quant Plasma

Clinical Info

Used in the diagnosis and monitoring of inherited disorders of fatty acid oxidation and organic acidurias. May be used as a follow-up test to some abnormal newborn screen results.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 mL plasma (minimum volume: 0.1 mL)

Container

Green Top Tube

Collection Instructions

 Container/Tube: Green-top (sodium heparin) Specimen: 1 mL plasma (minimum volume: 0.1 mL)
Transport Temperature: Frozen
Stability: 2 - 8 Weeks Frozen
 
Note: Centrifuge immediately after collection and pour off plasma in transport vial. Freeze immediately.

Transport Instructions

Frozen

Specimen Stability

2 - 8 Weeks Frozen
 
Note: Centrifuge immediately after collection and pour off plasma in transport vial. Freeze immediately.

Methodology

Flow injection/tandem mass spectrometry

Days Performed

TAT: 4-8 Days

Performing Laboratories

LabCorp

CPT

82017

PDM

5910515

Results
Component Name Base Name Common Name External Name
C2 C2 C2 C2
ACYL C3 ACYLC3 ACYL C3 C3
C3-DC C3DC C3 DC C3-Dicarboxylic
C4 C4 C4 C4
C4-OH C4OH C4 OH C4-Hydroxy
C4-DC C4D C4 DC C4-Dicarboxylic
C5 C5 C5 C5
C5:1 C5 C51 C5:1
C5-OH C5 C5 OH C5-Hydroxy
C5-DC C5 C5 DC C5-Dicarboxylic
C6 C6 C6 C6
C8 C8 C8 C8
C10 C10 C10 C10
C10:1 C10 C101 C10:1
C10:2 C10 C102 C10:2
C12 C12 C12 C12
C14 C14 C14 C14
C14:1 C141 C141 C14:1
C14:2 C142 C142 C14:2
C14-OH C14OH C14 OH C14-Hydroxy
C16 C16 C16 C16
C16:1 C16 C161 C16:1
C16:1-OH C16 C161 OH C16:1-Hydroxy
C16-OH C16 C16 OH C16-Hydroxy
C18 C18 C18 C18
C18:1 C181 C181 C18:1
C18:2 C182 C182 C18:2
C18-OH C18OH C18 OH C18-Hydroxy
C18:1-OH C181OH C181 OH C18:1-Hydroxy
C18:2-OH C182OH C182 OH C18:2-Hydroxy
INTERPRETATION ACP ACPINT INTERPRETATION ACP ACP Interpretation
DIRECTOR REVIEW ACP DIRREVIEW DIRECTOR REVIEW ACP ACP Director Review
METHODOLOGY ACP METHODOLOGY METHODOLOGY, ACP ACP Methodology
DISCLAIMER DISCLAIM DISCLAIMER Disclaimer

Result Interpretation

See report.   TAT 4 - 7 Days
  Units: umol/L
Includes:
C2  ,C3,  C3-Dicarboylic,  C4, C4-Hydroxy, C4-Dicarboxylic, C5, C5:1, c5-Hydroxy, C5-Dicarboxylic, C6, C8,  C10, C10:1, C10:2, C12, C14,  C14:1, C14:2 ,C14-Hydroxy,   C16, C16:1, C16:1-Hydroxy, C16-Hydroxy, C18, C18:1, C18:2, C18-Hydroxy, C18:1-Hydroxy, C18:2-Hydroxy  

 

Limitations
False-negative results can occur with acylcarnitine profiling, especially when the patient is carnitine deficient, is affected with a milder variant of a disorder, or when clinical condition or dietary supplementation causes secondary changes to the profile. Results of acylcarnitine profiling should be interpreted in the context of clinical presentation as well as other laboratory tests, which may include urine organic acid analysis and molecular testing.
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).       
            

Forms
Chemistry LAB429 build edit