FISH Solid Tumor
Synonyms |
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Cerner Name |
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Clinical Info |
This test is used for classification of certain tumors. MDM2 amplifications are frequently detected in well-differentiated liposarcoma (WDL), which includes atypical lipomatous tumor (ALT) and in dedifferentiated liposarcoma (DDL) |
Specimen Sources |
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Specimen Types |
Tissue |
Specimen Volume |
4 unstained slides of FFPE tissue section specimen 4-5 micron thick with two unique identifiers, block ID and cut number clearly labeled on the positively charged slides are required. An additional Hematoxylin and Eosin (H&E) slide must be submitted along with the sample clearly marked by a pathologist to denote the area of interest for the FISH study. |
Container |
Tissue block/Slides |
Collection Instructions |
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Transport Instructions |
Send slides to NSUH Cytogenetic laboratory ASAP at room temperature 20-25˚C. If there is a delay in transportation, store the sample ASAP at room temperature. |
Specimen Stability |
4-6 weeks room temperature |
Methodology |
Fluorescence in situ hybridization (FISH) on solid tumors in formalin-fixed paraffin- embedded (FFPE) tissue section specimens |
Days Performed |
Monday through Saturday; TAT: 7-10 Days |
Performing Laboratories |
Cytogenetics Laboratory at North Shore University Hospital (NSUH), Northwell Health Laboratories |
CPT |
88291 |
PDM |
258468 |
Results |
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Result Interpretation |
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Forms |
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