Inpatient and Outpatient Orderable

CXCR4 C1013G Mutation Analysis Build info

Synonyms

  • CXCR4 C1013G MUTATION ANALYSIS
  • LAB14273

Short Name

CXCR4 C1013G MUTATION ANALYSIS

Procedure Master Number

LAB14273

Procedure ID

184727

Clinical Info

CXCR4 C1013G Mutation Analysis
  CXCR4 C1013G mutation has been described as the most frequent recurrent
CXCR4 mutation identified in WM patients. Most of these cases
with CXCR4 mutations have concurrent MYD88 L265P mutations. This patient may
be eligible for treatment with ibrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor. CXCR4
mutations are associated with resistance to ibrutinib in patients with WM.

Specimen Sources

 Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous Bone Marrow

Specimen Types

 Blood Bone Marrow

Container

Lavender Top Tube

Collection Instructions

Container/Tube:  Lavender Top Tube
Specimen 1 - 3 mL Whole Blood or Bone Marrow

Transport Instructions

Room Temperature

Specimen Stability

Specimens are stable for a week refrigerated

Methodology

Allele Specific Real Time Polymerase Chain Reaction (RT-PCR)

Days Performed

Monday through Friday
TAT: 8 Calendar days

Performing Laboratory

Northwell Health Laboratories

CPT

81479

PDM

 248466

Only Orderable at Locations:

 Orderable Everywhere

Results