Cardio IQ Insulin Resistance Panel with Score

Synonyms

• CARDIO IQ INSULIN RESISTANCE PANEL WITH SCORE
• INSRESTIQ
• LAB14185

Cerner Name

Cardio IQ Insulin Resistance Panel with Score

Clinical Info

The determination of insulin in serum is primarily used for the diagnosis of glycemic disorders in diabetic and pre-diabetic
patients in the assessment of insulin resistant syndromes. Insulin is synthesized by the pancreatic beta cell as a precursor,
 proinsulin. Proinsulin is processed to insulin and C-peptide, a contiguous peptide between the insulin A and B chains, as
 it passes through the cell. The C-peptide in the proinsulin ensures correct folding and processing of proinsulin as it passes 
through the cell. Both insulin and C-peptide are released together from the beta cells in response to increased glucose levels. 
Because of differences in half-life and hepatic clearance, peripheral blood levels of C-peptide and insulin are no longer
equimolar but remain highly correlated. A steady-state plasma glucose test in individuals undergoing an insulin suppression 
test to assess insulin resistance found that the combination of insulin and C-peptide was a better indicator of insulin resistance 
than either one individually.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

0.5 mL serum ( 0.3 mL min)

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold Top Tube or Red Top Tube
Specimen: 0.5 mL serum ( 0.3 mL min)
Transport Temperature: Refrigerated
Note: Overnight fasting is required

Transport Instructions

Refrigerated

Specimen Stability

1 day Room Temperature
7 Days Refrigerated
28 Days Frozen

Methodology

Immunocapture Liquid Chromatography/Tandem Mass Spectrometry

Days Performed

TAT: 5-7 Days

Performing Laboratory

Quest Diagnostics Nichols Institute

CPT

83525
84681

PDM

235444

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms