Measurement of mid-trimester amniotic AFP fluid for detection of open neural tube defects and ventral wall defects. Samples with AFP values >= 2.0 MoM will reflex to detection of acetylcholinesterase and fetal hemoglobin.
Specimen Type
Other
Container
Screw Cap
Collection Instructions
Specimen: 3 mL Amniotic Fluid ( 2mL min) Patient Preparation: Patient must be between 15w0d and 21w6d at the time of amniocentesis. Optimally, the patient is between 15w0d and 18w6d. Avoid contamination of amniotic fluid with maternal or fetal blood. No other special preparation is required.
Specimen Rejection Criteria: Incorrect tube type Insufficient volume Fetal/Maternal blood contamination Out of gestational age range Special Instructions: The following Ask on Order Entry (AOE) patient information must be provided: Estimated Date of Delivery (EDD)
Transport Instructions
Room Temperature Refrigerated form overnight Delivery
Specimen Stability
7 days Room Temperature 30 Days Refrigerated
Methodology
Time-Resolved Amplified Cryptate Emission (TRACE)
This test was developed, and its performance characteristics determined by Northwell Health Laboratories. It has not been cleared or approved by the Food and Drug Administration. The methods and performance characteristics have been reviewed and approved by the New York State Department of Health.
