2T Maternal Serum Alpha Fetoprotein (AFP) Build info

Synonyms

  • 2T MATERNAL SERUM AFP
  • MSAFP
  • LAB14033

Short Name

2T MATERNAL SERUM AFP

Procedure Master Number

LAB14033

Procedure ID

182869

Clinical Info

Maternal serum AFP is a screening test for Open Neural Tube Defects (ONTD’S) such as
Open Spina Bifida (OSB) and Anencephaly. 
The test may also detect approximately 60% of Ventral Wall Defects
(VWD). A positive result means that further diagnostic testing may be offered
to the pregnant woman to determine if a structural defect is present.
MS-AFP is a screening test. 

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube Gold Top Tube( prefered)  or Red Top Tube
Collection Instructions
Specimen Rejection Criteria:  Incorrect tube type,  Insufficient volume,
                                               Fetal/maternal blood contamination
                                                Out of gestational age range
Special Instructions:
The following Ask on Order Entry (AOE) patient information must be provided:
 1: Maternal Weight
 2: Race/Ethnicity
 3: Estimated Date of Delivery (EDD)
 4: Gestational Age Method
 5: Current Smoker
 6: Multiple Pregnancy Status
 7: Insulin Dependent Diabetes
 8: Family History of ONTD
 9: Valproic Acid
10: Carbamazepine 
Complete information is necessary to interpret the test. Patient information may be
provided to the laboratory using the Maternal Prenatal Screening request form
(0900).
  Specimens must be collected before amniocentesis.
 
Maternal serum AFP screening is offered for gestational ages 15.0 to 21.9 weeks.
The optimal gestational age for maternal serum AFP is 16.0 to 18.9 weeks.  

Transport Instructions

Room Temperature
Refrigerated for overnight delivery.

Specimen Stability

6 Days Room Temperature
14 Days Refrigerated

Methodology

Time-Resolve Amplified Cryptate Emission (TRACE)
This test was developed, and its performance
characteristics determined by Northwell Health Laboratories. It has not been
cleared or approved by the Food and Drug Administration. The methods and
performance characteristics have been reviewed and approved by the New York
State Department of Health.

Days Performed

Monday - Friday   TAT: 1-2 Days upon receipt

Performing Laboratory

Northwell Core Lab at CFAM

CPT

82105

PDM

235467

Results
Component Name Base Name Common Name External Name
AFP CONCENTRATION AFPCONC AFP CONCENTRATION Afp Concentration
AFP INTERPRETATION AFPINTERP AFP INTERPRETATION Afp Interpretation
AFP MOM AFPMOM AFP MOM
AFP MOM CUT-OFF AFPMOMCUT AFP MOM CUT OFF Afp Mom Cut-Off
AFP PERCENTILE AFPPCT AFP PERCENTILE Afp Percentile
AFP VALUE AFPVALUE AFPVALUE Afp Value
AFTER SCREENING RISK OPEN SPINA BIFIDA RISKOSB AFTER SCREENING RISK OPEN SPINA BIFIDA After Screening Risk Open Spina Bifida
BEFORE SCREENING RISK OPEN SPINA BIFIDA RISKOSB BEFORE SCREENING RISK OPEN SPINA BIFIDA Before Screening Risk Open Spina Bifida
EXTREME ANALYTE ALERT EXTANAALRT EXTREME ANALYTE ALERT Extreme Analyte Alert
GEN TEST INFORMATION GENTEST GEN TEST INFORMATION Gen Test Information
GESTATIONAL AGE GESTAGE GESTATIONAL AGE Gestational Age
GESTATIONAL AGE BASED ON GESTAGE GESTATIONAL AGE BASED ON Gestational Age Based On
INITIAL OR REPEAT TESTING INITIAL OR REPEAT TESTING Initial or Repeat Testing?
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome
PREV PREG WITH DOWN SYNDROME PREVPREGDOWN PREV PREG WITH DOWN SYNDROME Prev Preg With Down Syndrome