Factor 5 Leiden Mutation Molecular Detection

Synonyms

• ACTIVATED PROTEIN C RESISTANCE
• FACTOR V LEIDEN
• FACTOR V, THROMBOPHILIA, ACTIVATED PROTEIN C RESISTANCE MUTATION, FVL R506Q MUTATION TESTING
• LAB346
• MUTATION

Cerner Name

HLX Factor V Leiden CASE

Clinical Info

A single point mutation in exon 10 of Factor V gene leads to a pro-thrombotic state. The incidence of this mutation in the general population is 3-8% (depending on ethnicity).  Caucasians are the most affected.  Factor V Leiden has been estimated to be present in 15 to 20 percent of patients with first venous thromboembolism, VTE and is the most common heritable pro-thrombotic risk factor in the United States.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

Container

Collection Instructions

Container/Tube: Lavender-top (EDTA) tube(s)
Specimen Volume: 1-3 mL of peripheral blood
Transport Temperature:  Room Temperature
 
Note: Pertinent medical information including patient’s age, suspected diagnosis and a signed Patient Consent Form are required.

Transport Instructions

Room Temperature

Specimen Stability

Specimens are stable for a week refrigerated.

Methodology

Real-Time PCR

Days Performed

Monday through Friday
TAT: 8 Calendar days

Performing Laboratory

Northwell Health Laboratories

CPT

81241

PDM

5160174

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms