Factor 5 Leiden Mutation Molecular Detection Build info

Synonyms

  • FACTOR V LEIDEN
  • MUTATION
  • FACTOR V, THROMBOPHILIA, ACTIVATED PROTEIN C RESISTANCE MUTATION, FVL R506Q MUTATION TESTING
  • ACTIVATED PROTEIN C RESISTANCE
  • LAB346

Short Name

FACTOR V LEIDEN

Procedure Master Number

LAB346

Procedure ID

1802

Clinical Info

A single point mutation in exon 10 of Factor V gene leads to a pro-thrombotic state. The incidence of this mutation in the general population is 3-8% (depending on ethnicity).  Caucasians are the most affected.  Factor V Leiden has been estimated to be present in 15 to 20 percent of patients with first venous thromboembolism, VTE and is the most common heritable pro-thrombotic risk factor in the United States.

Specimen Type

Blood

Container

Collection Instructions

Container/Tube: Lavender-top (EDTA) tube(s)
Specimen Volume: 1-3 mL of peripheral blood
Transport Temperature:  Room Temperature
 
Note: Pertinent medical information including patient’s age, suspected diagnosis and a signed Patient Consent Form are required.

Transport Instructions

Room Temperature

Specimen Stability

Specimens are stable for a week refrigerated.

Methodology

Real-Time PCR

Days Performed

Monday through Friday
TAT: 8 Calendar days

Performing Laboratory

Northwell Health Laboratories

CPT

81241

PDM

5160174

Results