Adalimumab and Anti-Adalimumab Antibody (DoseAssure)

Synonyms

  • ADALIMAMAB
  • ADALIMAUMAB AB
  • ADALIMUMAB LEVEL AND ANTIBODY
  • LAB10041

Cerner Name

Adalimumab and Adalimumab Ab

Clinical Info

Monitor antiadalimumab therapy for individuals with Crohn's disease, inflammatory bowel disease, ulcerative colitis, rheumatoid arthritis, or other autoimmune conditions. This test provides adalimumab drug concentration levels as well as the level of antiadalimumab antibodies.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

2 mL serum (1 mL min)

Container

Gold Top Tube

Collection Instructions

Container/Tube: Red top or Gold top tube
Specimen: 2ml serum (1 mL min)
Transport Temperature: Frozen

Transport Instructions

Frozen

Specimen Stability

7 Days Room Temperature
7 Days Refrigerated
308 Days Frozen

Methodology

Electrochemiluminescence immunoassay (ECLIA)

Days Performed

TAT: 7-10 Days

Performing Laboratories

LabCorp of America

CPT

80145
82397
LOINC Code: 99781-7

PDM

5903888

Results
Component Name Base Name Common Name External Name
ADALIMUMAB DRUG LEVEL ADALIMDRUG ADALIMUMAB DRUG LEVEL Adalimumab Drug Level
ANTI-ADALIMUMAB ANTIBODY AADALIMUMAB ANTI ADALIMUMAB AN Anti-Adalimumab Antibody

Result Interpretation

Adalimumab Drug Level
• Quantitation limit: <0.6 μg/mL

• Results ≥0.6 μg/mL indicate detection of adalimumab.

In the presence of antiadalimumab antibody, the adalimumab drug level reflects the antibody-unbound fraction of adalimumab concentration in serum.
Antiadalimumab Antibody
 
• Quantitation limit: <25 ng/mL

• Results ≥25 ng/mL indicate detection of adalimumab antibody.

Forms
Tox/TDM LAB10041 build edit