Cortisol and Cortisone, Saliva

Synonyms

• CORTISOL, SALIVARY
• LAB10005
• SALIVARY CORTISOL

Cerner Name

Salivary Cortisol

Clinical Info

Screening for Cushing syndrome
Diagnosis of Cushing syndrome in patients presenting with symptoms or signs suggestive of the disease

Specimen Sources

Salivary

Specimen Types

Saliva

Specimen Volume

Specimen Volume: 1.5 mL (Min 0.6 mL)

Container

Sarstedt Salivette

Collection Instructions

Patient Preparation:
1. Patient should not brush teeth, eat, drink, or take any oral medication for at least 60 minutes before specimen collection.

2. Have patient rinse mouth thoroughly with water for 1 to 5 seconds. Wait 10 minutes before collecting the specimen to avoid contamination of the saliva by an interfering substance.

Collection Instructions:


1. Provide patient with a Saliva Collection Kit (Salivette) containing the Cortisol and Cortisone - Saliva Collection Instructions and ask them to follow the instructions as written.

2. If performing a late-night salivary cortisol (LNSC) test, specimen should be collected immediately prior to going to bed. If patient is undergoing assessment for adrenal insufficiency, specimen should be collected immediately after waking up. The patient should follow their normal sleeping schedule.

3. Instruct patient to return the appropriately labeled Salivette to the laboratory.

Transport Instructions

Refrigerated

Specimen Stability

28 Days Room Temperature or Refrigerated
60 Days Frozen

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

Monday, Wednesday, Friday; 4 p.m.

Performing Laboratories

Mayo Medical Laboratories

CPT

82530,82542

PDM

5901372

Results

Result Interpretation

Forms

• Cortisol and Cortisone Saliva Collection Instructions