Screening for Cushing syndrome Diagnosis of Cushing syndrome in patients presenting with symptoms or signs suggestive of the disease
Specimen Type
Body Fluid
Container
Collection Instructions
Patient Preparation: 1. Do not brush teeth before collecting specimen. 2. Do not eat or drink for 15 minutes prior to specimen collection. Supplies: Cortisol, Saliva Collection Kit (T514) Container/Tube: SARSTEDT Salivette Specimen Volume: 1.5 mL Collection Instructions: 1. Provide patient with a Saliva Collection Kit (Salivette) containing the Cortisol - Saliva Collection Instructions and ask them to follow the instructions as written. 2. Instruct patient to collect specimen between 11 p.m. and midnight and record collection time on specimen Additional Information: 1. Reference values are also available for an 8 a.m. (7 a.m.-9 a.m.) or a 4 p.m. (3 p.m.-5 p.m.) collection, however, the 11 p.m. to midnight collection is preferred. 2. If multiple specimens are collected, submit each vial under a separate order. Specimen Type Saliva Transport Temperature: Refrigerated Stability: 28 Days Room Temperature or Refrigerated 60 Days Frozen
Transport Instructions
Refrigerated
Specimen Stability
28 Days Room Temperature or Refrigerated 60 Days Frozen
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
