KIT D816V
Test Catalog Information
| Test Catalog Synonyms | |
| EPIC Synonyms |
KIT D816V Systemic Mastocystosis C-KIT |
| Cerner Primary Mnemonic | KIT D816V |
| EPIC Display Name | KIT D816V |
| Allscripts (AEHR) Order Name | KIT D816V |
| Sunrise Clinical Manager (SCM) Order Name | KIT D816V |
| EPIC Inpatient Orderable | Yes |
| EPIC Outpatient Orderable | Yes |
| Cerner Results |
C-KIT (D816V) |
| Clinical Info |
Systemic mastocytosis is characterized by the infilitration of clonal mast cells in the bone marrow, tissue, liver, and skin. Mutational testing for KIT D816V is a diagnostic tool for systemic mastocytosis because the majority of confirmed diagnoses harbor this mutation. Bone marrow evaluation is the primary diagnostic tool for systemic mastocytosis and provides the most reliable prognosis. Patients that harbor the KIT mutation exhibit resistance to tyrosine kinase inhibitor therapy, such as imatinib. When KIT is mutated in the presence of RUNX1 the patient prognosis is unfavorable. |
| Specimen Type | |
| Container |
Green Top Tube |
| Collection Instructions |
Container/Tube: Lavender(EDTA) Top Tube- Peripheral blood Dark Green Top- Bone Marrow Specimen: 5 mL Peripheral Blood 2 mL Bone Marrow Transport Temperature: Room Temperature |
| Transport Instructions |
Room Temperature |
| Specimen Stability | |
| Methodology |
Pyrosequencing |
| Days Performed |
TAT: 5 -6 Days |
| Performing Laboratory |
BioReference Laboratories |
| CPT |
81273 LOINC Code: 51185-7 |
| PDM |
235036 |
Desired Epic Build KIT D816V
| Cerner Primary Mnemonic: | KIT D816V | ||||||
| PDM | 235036 | ||||||
| Informatics - Workgroup | Molecular-send outs | ||||||
| Synonyms * | KIT D816V Systemic Mastocystosis C-KIT | ||||||
| Display Name * | KIT D816V | ||||||
| Order Entry Specimen Sources * | |||||||
| Order Entry Specimen Types |
Blood
Bone Marrow
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| Ordering info (EPIC SmartText) | Systemic mastocytosis is characterized by the infilitration of clonal mast cells in the bone marrow, tissue, liver, and skin. Mutational testing for KIT D816V is a diagnostic tool for systemic mastocytosis because the majority of confirmed diagnoses harbor this mutation. Bone marrow evaluation is the primary diagnostic tool for systemic mastocytosis and provides the most reliable prognosis. Patients that harbor the KIT mutation exhibit resistance to tyrosine kinase inhibitor therapy, such as imatinib. When KIT is mutated in the presence of RUNX1 the patient prognosis is unfavorable. | ||||||
| IP Orderable | Yes | ||||||
| OP Orderable | Yes | ||||||
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AOEs * | |||||||
| AP AOEs | |||||||
| Special History | No | ||||||
| Build Comments | |||||||
| Filter * | genetics | ||||||
| Procedure Category Change | |||||||
Cerner Results
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Current Actual EPIC Build as of 10/28/2024
| Procedure Id | 137039 | ||||||||||||
| Pdm | 235036 | ||||||||||||
| Order Display Name | KIT D816V | ||||||||||||
| Procedure Name | KIT D816V | ||||||||||||
| Procedure Master Number | LAB12483 | ||||||||||||
| Short Procedure Name | KIT D816V | ||||||||||||
| Category Code | 1.0 | ||||||||||||
| Category Code Record Name | LAB BLOOD ORDERABLES | ||||||||||||
| Synonyms | KIT D816V Systemic Mastocystosis C-KIT | ||||||||||||
| Clinically Active | Yes | ||||||||||||
| Orderable | Yes | ||||||||||||
| Performable | Yes | ||||||||||||
| Filter Genomics | Generic Genomics Procedure | ||||||||||||
| Reference Link Url | https://labs.northwell.edu/epic/test/137039 | ||||||||||||
| Ordering Instructions | |||||||||||||
| Default Specimen Type | Blood | ||||||||||||
| Specimen Type Pick List | Bone Marrow Blood | ||||||||||||
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| Op Specimen Type List | |||||||||||||
| Specimen Source Pick List | Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous Bone Marrow Aspirate | ||||||||||||
| Specimen Source Default - Male | Blood, Venous | ||||||||||||
| Specimen Source Default - Female | Blood, Venous | ||||||||||||
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| Ip Lab Test Components For Report | |||||||||||||
| Op Lab Test Components For Report | |||||||||||||
| Order Questions | [] | ||||||||||||
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| Inpatient Order Questions | [] | ||||||||||||
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| Edp Ip Specimen Source | Blood, Venous Blood, Central Line Blood, Arterial Blood, Capillary | ||||||||||||
| Edp Op Specimen Source | |||||||||||||
| Edp Ip Specimen Type | Blood | ||||||||||||
| Edp Op Specimen Type | |||||||||||||
| Derived Edp Ip Buttons S | Blood, Central Line Blood, Venous Blood, Capillary Blood, Arterial | ||||||||||||
| Derived Edp Ip Buttons T | Blood | ||||||||||||
| Derived Edp Op Buttons S | |||||||||||||
| Derived Edp Op Buttons T | |||||||||||||
| Ip Orderable | 1 | ||||||||||||
| Op Orderable | 1 | ||||||||||||
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EPIC Components (results)
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