Synonyms
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- CMV INSIGHT T CELL IMMUNITY
- CMVTCELL
- LAB12448
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Cerner Name
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CMV inSIGHT T Cell Immunity
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Clinical Info
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*** Must be delivered STAT to Lab ***
URGENT!! Extremely limited sample stability. Blood must be drawn Monday through Thursday after 8:00 AM and before 12 PM. Samples MUST be received at CFAM by 12:00 PM (noon), Monday to Thursday only. DO NOT draw if the patient arrives after 12:00 PM. Reschedule patient if they arrive after 12 PM. Request STAT pickup by emailing NorthwellLogistics@northwell.edu and copy CoreReferenceDept@northwell.edu for increased awareness
The CMV inSIGHT™ T Cell Immunity Panel measures the strength of T cell responses to Cytomegalovirus (CMV) specific antigens. It evaluates and reports the activity of CD4 and CD8 T cell responses independently. Effective T cell immunity against CMV is a factor in controlling CMV viral latency. CMV can affect patients with weakened immune systems and is a common risk factor in patients following solid organ or hematopoietic stem cell transplant.
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Specimen Sources
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Blood, Arterial
Blood, Capillary
Blood, Central Line
Blood, Venous
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Specimen Types
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Blood
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Specimen Volume
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10 mL Whole Blood Dark Green Top Tube FULL (7.5 mL min)
Pediatric Patients: Whole Blood 4 mL min volume.
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Container
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Dark Green Sodium Heparin Tube
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Collection Instructions
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URGENT!! Extremely limited sample stability. Blood must be drawn Monday through Thursday after 8:00 AM and before 12 PM. Samples MUST be received at CFAM by 12:00 PM (noon), Monday to Thursday only. DO NOT draw if the patient arrives after 12:00 PM. Reschedule patient if they arrive after 12 PM. Request STAT pickup by emailing NorthwellLogistics@northwell.edu and copy CoreReferenceDept@northwell.edu for increased awareness.
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Transport Instructions
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Note: Blood must be drawn Monday through Thursday only.DO NOT SHIP on days when a holiday follows within 2 days of the shipping day.Ship samples priority overnight Monday through Thursday, at ambient temperature on the same day as collection.
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Specimen Stability
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24 Hours Room Temperature
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Methodology
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Whole blood is stimulated with SEB, CMV antigens, or left unstimulated as a negative control and incubated at 37ºC. During the incubation Brefeldin A is added, causing the interferon (IFN)-gamma to be retained inside the cell. Following the stimulation phase, cells are recovered, stained for surface markers (CD3, CD4, CD8, CD69) and intracellular IFN-gamma, and analyzed by flow cytometry. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.
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Days Performed
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TAT: 4-5 Days
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Performing Laboratories
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Viracor-Euofins
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CPT
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86352 x 4
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PDM
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235609
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Results
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| Component Name |
Base Name |
Common Name |
External Name |
| % CD4 CMV INTERFERON-GAMMA CELLS |
PCTCD4CMV |
PCT CD4 CMV INTERFERON GAMMA CELLS |
% CD4 CMV Interferon-gamma Cells |
| % CD8 CMV INTERFERON-GAMMA CELLS |
PCTCD8CMV |
PCT CD8 CMV INTERFERON GAMMA CELLS |
% CD8 CMV Interferon-gamma Cells |
| % CD4 SEB INTERFERON-GAMMA CELLS |
PCTCD4SEB |
PCT CD4 SEB INTERFERON GAMMA CELLS |
% CD4 SEB Interferon-gamma Cells |
| % CD8 SEB INTERFERON-GAMMA CELLS |
PCTCD8SEB |
PCT CD8 SEB INTERFERON GAMMA CELLS |
% CD8 SEB Interferon-gamma Cells |
| VIABILITY |
VIABILITY |
VIABILITY |
Viability |
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Result Interpretation
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Forms
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