Copeptin, Plasma

Synonyms

  • COPEPTIN, PLASMA
  • LAB12063

Cerner Name

Copeptin,Plasma

Clinical Info

Investigating the differential diagnosis for patients with water balance disorders, including diabetes insipidus, in 
conjunction with osmolality and hydration status

May aid in the evaluation of cardiovascular disease in conjunction with other cardiac markers

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

0.5 mL Plasma (0.3 mL min)

Container

Lavender Top Tube

Collection Instructions

Container/Tube; Lavender Top (EDTA) Tube
Specimen: 0.5 mL Plasma ( 0.3 mL min)
Transport Temperature: Refrigerated
Patient Preparation: For water-deprived testing, have the patient fast and thirst for at least
                                  8 hours (no liquids, including water, are allowed)

Transport Instructions

Refrigerated

Specimen Stability

7 Days Room Temperature
7 Days Refrigerated
30 Days Frozen

Methodology

Immunofluorescent Assay (IFA)

Days Performed

TAT 2-4 Days

Performing Laboratories

Mayo Medical Laboratories

CPT

84588
LOINC Code 78987-5

PDM

235441

Results

Component Name Base Name Common Name External Name
COPEPTIN,PLASMA COPEPTIN COPEPTIN, PLASMA Copeptin,Plasma

Result Interpretation

Non-water deprived, non-fasting adults*: <13.1 pmol/L

Water deprived, fasting adults**: <15.2 pmol/L

Non-water deprived, non-fasting pediatric patients***: <14.5 pmol/L

Note:

*Keller T, Tzikas S, Zeller T, et al: Copeptin improves early diagnosis of acute myocardial infarction. J Am Coll Cardiol. 2010 May 11;55[19]:2096-2106. doi: 10.1016/j.jacc.2010.01.029

**In-house Mayo study.

***Du JM, Sang G, Jiang CM, He XJ, Han Y: Relationship between plasma copeptin levels and complications of community-acquired pneumonia in preschool children. Peptides. 2013 Jul;45:61-65. doi: 10.1016/j.peptides.2013.04.015

Forms

Chemistry LAB12063 build edit