HIV-1 Resistance, Proviral DNA (RTI, PI, Integrase Inhibitors) (Quest)

Synonyms

• HIV-1 GENOTYPE (RTI,PI,INTEGRASE INHIBITORS)
• LAB11784

Cerner Name

HIV-1 Genotype (RTI,PI,Integrase Inhibitors)

Clinical Info

Identify drug resitance mutations in HIV-1 patients failing antiretroviral regimens containing RT, PR or Integrase inhibitors. Identify transmitted drug resistance mutations in the RT, PR or integrase genes in treatment-naive patients prior to initiation of antiretroviral therapy.

Specimen Sources

Blood, Venous

Specimen Types

Blood

Specimen Volume

4 mL plasma ( 1.2 mL min)

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender top tube or PPT (white top tube)
Specimen: 4 mL plasma ( 1.2 mL min)
Transport Temperature: Frozen
Stability:  Room temperature: 24 hours
                 Refrigerated: 6 days
                 Frozen: 42 days
 
Collection Instructions
Freshly drawn specimens (whole blood) may be stored at 2°C to 25°C for up to 24 hours prior to centrifugation. Separate plasma from cells within 24 hours of collection by centrifugation..

Transport Instructions

Frozen

Specimen Stability

Room temperature: 24 hours
                 Refrigerated: 6 days
                 Frozen: 42 days
 
Collection Instructions
Freshly drawn specimens (whole blood) may be stored at 2°C to 25°C for up to 24 hours prior to centrifugation

Methodology

Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) • Sequencing
Includes
HIV-1 Integrase Genotype HIV-1 Genotype

Days Performed

Performing Laboratories

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

CPT

87900
87901
87906

PDM

5920205

Results

Result Interpretation

Forms