Human Leukocyte Antigens (HLA) A-B-C Disease Association Typing Low Resolution

Synonyms

  • HLA CLASS A-B-C DISEASE ASSO.
  • HLA-ABC
  • LAB11603

Cerner Name

HLA Class A-B-C Disease Asso.

Clinical Info

Determining class I human leukocyte antigens (HLA) on specimens for those patients
who have become refractory to platelet transfusions and identify potential disease association
Human leukocyte antigens (HLA) are regulators of the immune response.
HLA class I typing is used to identify HLA-matched platelets for alloimmunized
refractory patients and identify presence of HLA antigens associated with a
number of diseases or as drug hypersensitivity markers Class I HLA antigens
include A, B, and C loci. This assay is designed to provide low-to-medium
resolution for HLA class I typing (A, B, C). Low-to-medium resolution defines
the typing at the antigen level (first field). This is in contrast to high-resolution
typing, which defines typing at the allele (molecular) level (second field or higher).

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

6 mL whole Blood ( 3 mL min)

Container

Acd/Yellow

Collection Instructions

Container/Tube: Yellow top (ACD solution B)
Specimen: 6 mL whole Blood ( 3 mL min)
Transport Temperature: Room Temperature
Instructions: Do not transfer blood to other containers.
Additional
Information: Specimen acceptability is based on extracted DNA
concentration and not sample age

Transport Instructions

Room Temperature

Specimen Stability

Methodology

Polymerase Chain Reaction (PCR)/Sequence-Specific Oligonucleotide Probes (SSO)

Days Performed

Performing Laboratories

Mayo Medical Laboratories
Mayo Code 1DIS

CPT

81372

PDM

2059436

Results
Component Name Base Name Common Name External Name
ABC DISASSOC COMMENT ABCDISASSCOM ABC DISASSOC COMMENT ABC DisAssoc Comment
A - 1 EQUIVALENT A1EQUIV A 1 EQUIVALENT A - 1 Equivalent
A - 2 EQUIVALENT A2EQUIV A 2 EQUIVALENT A - 2 Equivalent
A - 1 MOLECULAR A1MOLEC A 1 MOLECULAR A - 1 Molecular
A - 2 MOLECULAR A2MOLEC A 2 MOLECULAR A - 2 Molecular
B - 1 EQUIVALENT B1EQUIV B 1 EQUIVALENT B - 1 Equivalent
B - 2 EQUIVALENT B2EQUIV B 2 EQUIVALENT B - 2 Equivalent
B - 1 MOLECULAR B1MOLEC B 1 MOLECULAR B - 1 Molecular
B - 2 MOLECULAR B2MOLEC B 2 MOLECULAR B - 2 Molecular
BW - 1 EQUIVALENT BW1EQUIV BW 1 EQUIVALENT Bw - 1 Equivalent
BW - 2 EQUIVALENT BW2EQUIV BW 2 EQUIVALENT Bw - 2 Equivalent
C - 1 EQUIVALENT C1EQUIV C 1 EQUIVALENT C - 1 Equivalent
C - 2 EQUIVALENT C2EQUIV C 2 EQUIVALENT C - 2 Equivalent
C - 1 MOLECULAR C1MOLEC C 1 MOLECULAR C - 1 Molecular
C - 2 MOLECULAR C2MOLEC C 2 MOLECULAR C - 2 Molecular
TEST METHOD TESTMETH TEST METHOD Test Method

Result Interpretation

Forms
Molecular-send outs LAB11603 build edit