Dihydropyrimidine Dehydrogenase (DPYD) Gene Mutation Analysis
Test Catalog Information
| Test Catalog Synonyms | |
| EPIC Synonyms |
Dihydropyrimidine Dehydrogenase (DPD) Gene Mutation Analysis DPD Gene Mutation Analysis |
| Cerner Primary Mnemonic | zzzDihydropyrimidine Dehydrogenase (DPD) Gene Mutation Analysis |
| EPIC Display Name | Dihydropyrimidine Dehydrogenase (DPYD) Gene Mutation Analysis |
| Allscripts (AEHR) Order Name | Dihydropyrimidine Dehydrogenase (DPD) Gene Mutation Analysis |
| Sunrise Clinical Manager (SCM) Order Name | Dihydropyrimidine Dehydrogenase (DPD) Gene Muta |
| EPIC Inpatient Orderable | No |
| EPIC Outpatient Orderable | No |
| Cerner Results | |
| Clinical Info |
Partial or complete deficiency of DPD activity has been associated with an increased risk for severe adverse reactions when treated with pyrimidine-based chemotherapeutic agents, such as 5-fluorouracil (5-FU). The test can also be used to confirm the clinical diagnosis of dihydropyrimidine dehydrogenase (DPD) deficiency in affected patients and for the dectection of the IVS14+1G→A mutation in asymptomatic carriers |
| Specimen Type | |
| Container |
Lavender Top Tube |
| Collection Instructions |
Container/Tube: Lavender (EDTA) top tube or ACD solution B Yellow top tube |
| Transport Instructions |
Room Temperature |
| Specimen Stability |
8 days Room Temperature or Refrigerated |
| Methodology |
Polymerase Chain Reaction (PCR) • Single Nucleotide Primer Extension This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes |
| Days Performed |
Monday - Thursday |
| Performing Laboratory |
Quest Diagnostics' Nichols Institute, Inc. - Chantilly |
| CPT |
81232 |
| PDM |
1759550 |
Desired Epic Build Dihydropyrimidine Dehydrogenase (DPYD) Gene Mutation Analysis
| Cerner Primary Mnemonic: | zzzDihydropyrimidine Dehydrogenase (DPD) Gene Mutation Analysis |
| PDM | 1759550 |
| Informatics - Workgroup | Molecular-send outs |
| Synonyms * | Dihydropyrimidine Dehydrogenase (DPD) Gene Mutation Analysis DPD Gene Mutation Analysis |
| Display Name * | Dihydropyrimidine Dehydrogenase (DPYD) Gene Mutation Analysis |
| Order Entry Specimen Sources * | |
| Order Entry Specimen Types |
Blood
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| Specimen Navigator Specimen Types | |
| Specimen Navigator Specimen Sources | |
| Specimen Navigator Short Name | |
| Ordering info (EPIC SmartText) | Partial or complete deficiency of DPD activity has been associated with an increased risk for severe adverse reactions when treated with pyrimidine-based chemotherapeutic agents, such as 5-fluorouracil (5-FU). The test can also be used to confirm the clinical diagnosis of dihydropyrimidine dehydrogenase (DPD) deficiency in affected patients and for the dectection of the IVS14+1G→A mutation in asymptomatic carriers |
| IP Orderable | No |
| OP Orderable | No |
|
AOEs * | |
| AP AOEs | |
| Special History | No |
| Build Comments | |
| Filter * | genetics |
| Procedure Category Change | |
| Cerner Results | |
Current Actual EPIC Build as of 10/28/2024
| Procedure Id | 115493 | ||||||||||||
| Pdm | 1759550 | ||||||||||||
| Order Display Name | Dihydropyrimidine Dehydrogenase (DPYD) Gene Mutation Analysis | ||||||||||||
| Procedure Name | DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) GENE MUTATION ANALYSIS | ||||||||||||
| Procedure Master Number | LAB11589 | ||||||||||||
| Short Procedure Name | DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) GENE MUTATION ANALYSIS | ||||||||||||
| Category Code | 15.0 | ||||||||||||
| Category Code Record Name | LAB CYTOGENETICS ORDERABLES | ||||||||||||
| Synonyms | DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) GENE MUTATION ANALYSIS DPD GENE MUTATION ANALYSIS | ||||||||||||
| Clinically Active | No | ||||||||||||
| Orderable | No | ||||||||||||
| Performable | No | ||||||||||||
| Filter Genomics | Generic Genomics Procedure | ||||||||||||
| Reference Link Url | https://labs.northwell.edu/epic/test/115493 | ||||||||||||
| Ordering Instructions | |||||||||||||
| Default Specimen Type | Blood | ||||||||||||
| Specimen Type Pick List | Blood | ||||||||||||
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| Specimen Source Pick List | Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous | ||||||||||||
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| Order Questions | ["3048500000"] | ||||||||||||
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| Inpatient Order Questions | ["3048500000"] | ||||||||||||
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| Edp Amb Order Specific Questions Record Name | NH IP PATIENT COMPLETED CONSENT | ||||||||||||
| Edp Ip Order Specific Questions Record Name | NH IP PATIENT COMPLETED CONSENT | ||||||||||||
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| Ip Orderable | 0 | ||||||||||||
| Op Orderable | 0 | ||||||||||||
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