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HLA B*58:01, Allopurinol Hypersensitivity

Test Catalog Information

Test Catalog Synonyms
EPIC Synonyms HLAB58
Cerner Primary MnemonicHLA B*58:01
EPIC Display NameHLA B*58:01, Allopurinol Hypersensitivity
Allscripts (AEHR) Order Name

HLA B*58:01

Sunrise Clinical Manager (SCM) Order Name

HLA B*58:01

EPIC Inpatient Orderable Yes
EPIC Outpatient Orderable Yes
Cerner Results HLABR
HLAB
HLAMETHOD
Clinical Info

Allopurinol associated SCAR (severe cutaneous adverse drug reaction) including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has been shown to be associated with the human leukocyte antigen (HLA) B*58:01 of the major histocompatibility complex (MHC). The MHC family of genes codes for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T-cell receptors to elicit an immune response. The presence of the HLA B*58:01 allele increases the susceptibility to allopurinol SCAR in several populations studied.

Specimen Type

Blood

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender Top tube Specimen: 7 mL whole Blood ( 7 mL min) Transport Temperature: Room Temperature Stability: Maintain at Room Temperature or Refrigerated

Transport Instructions

Room Temperature

Specimen Stability

Maintain at Room Temperature or Refrigerated

Methodology

Sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution

Days Performed

TAT: 4-8 Days

Performing Laboratory

LabCorp

CPT

81381 LOINC Code: 13299-3

PDM

225201

Desired Epic Build HLA B*58:01, Allopurinol Hypersensitivity

Cerner Primary Mnemonic: HLA B*58:01
PDM 225201
Informatics - WorkgroupMolecular-send outs
Synonyms *HLAB58
Display Name *HLA B*58:01, Allopurinol Hypersensitivity
Order Entry Specimen Sources *
Order Entry Specimen Types
Blood
Specimen Navigator Specimen Types
Specimen Navigator Specimen Sources
Specimen Navigator Short Name
Ordering info (EPIC SmartText) Allopurinol associated SCAR (severe cutaneous adverse drug reaction) including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has been shown to be associated with the human leukocyte antigen (HLA) B*58:01 of the major histocompatibility complex (MHC). The MHC family of genes codes for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T-cell receptors to elicit an immune response. The presence of the HLA B*58:01 allele increases the susceptibility to allopurinol SCAR in several populations studied.
IP Orderable Yes
OP Orderable Yes
AOEs *

AP AOEs
Special History No
Build Comments
Filter *genetics
Procedure Category Change
Cerner Results

Result DescResult displayResult PDM
HLABR HLABR 225201B
HLAB HLAB 225201A
HLAMETHOD HLAMETHOD 2059703C

Current Actual EPIC Build as of 10/28/2024

Procedure Id 115423
Pdm 225201
Order Display Name HLA B*58:01, Allopurinol Hypersensitivity
Procedure Name HLA B*58:01
Procedure Master Number LAB11554
Short Procedure Name HLA B*58:01
Category Code 15.0
Category Code Record Name LAB CYTOGENETICS ORDERABLES
Synonyms HLAB58
Clinically Active Yes
Orderable Yes
Performable Yes
Filter Genomics Generic Genomics Procedure
Reference Link Url https://labs.northwell.edu/epic/test/115423
Ordering Instructions
Default Specimen Type Blood
Specimen Type Pick List Blood
Specimen Type List
Op Specimen Type List
Specimen Source Pick List Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous
Specimen Source Default - Male Blood, Venous
Specimen Source Default - Female Blood, Venous
Specimen Source List
Op Specimen Source List
Ip Lab Test Components For Report
Op Lab Test Components For Report
Order Questions ["3045300170", "3045300171", "3045300173"]
Order Questions Record Name NH IP HOME COLLECT DATE NH IP HOME COLLECT DAYS NH IP HOME COLLECT MEDICALLY NECESSARY
Inpatient Order Questions ["3048500000"]
Inpatient Order Questions Record Name
Order Specific Question Override Yes
Inpatient Question Override
Location Restrict List Ip
Location Restrict List Ip Record Name
Location Restrict List Include Ip
Location Restrict List Op
Location Restrict List Op Record Name
Location Restrict List Includes Op
Edp Amb Order Specific Questions Record Name NH IP PATIENT COMPLETED CONSENT
Edp Ip Order Specific Questions Record Name NH IP PATIENT COMPLETED CONSENT
Edp Ip Specimen Source
Edp Op Specimen Source
Edp Ip Specimen Type
Edp Op Specimen Type
Derived Edp Ip Buttons S
Derived Edp Ip Buttons T
Derived Edp Op Buttons S
Derived Edp Op Buttons T
Ip Orderable 1
Op Orderable 1
EPIC OP AOEs

Question IDQuestion NameQuestionResponse TypeResponse ListRequire Response
3045300170 NH IP HOME COLLECT DATE Start Date Date Yes
3045300171 NH IP HOME COLLECT DAYS Days Custom List Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Yes
3045300173 NH IP HOME COLLECT MEDICALLY NECESSARY Medically Necessary? Yes/No Yes
EPIC IP AOEs

Question IDQuestion NameQuestionResponse TypeResponse ListRequire Response
3048500000 NH IP PATIENT COMPLETED CONSENT Patient completed consent? Yes/No Yes
EPIC Components (results)

Component IDComponent NameBase NameCommon NameExternal NameCerner Result PDM
3047802857 HLAB RESULTS HLABRES HLAB RESULTS 225201B
3047802852 HLA-B HLAB HLA B 225201A
3047802851 HLA METHODOLOGY HLAMETH HLA METHODOLOGY 2059703C