HLA B*58:01, Allopurinol Hypersensitivity
Test Catalog Information
Test Catalog Synonyms | |
EPIC Synonyms | HLAB58 |
Cerner Primary Mnemonic | HLA B*58:01 |
EPIC Display Name | HLA B*58:01, Allopurinol Hypersensitivity |
Allscripts (AEHR) Order Name | HLA B*58:01 |
Sunrise Clinical Manager (SCM) Order Name | HLA B*58:01 |
EPIC Inpatient Orderable | Yes |
EPIC Outpatient Orderable | Yes |
Cerner Results |
HLABR HLAB HLAMETHOD |
Clinical Info |
Allopurinol associated SCAR (severe cutaneous adverse drug reaction) including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has been shown to be associated with the human leukocyte antigen (HLA) B*58:01 of the major histocompatibility complex (MHC). The MHC family of genes codes for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T-cell receptors to elicit an immune response. The presence of the HLA B*58:01 allele increases the susceptibility to allopurinol SCAR in several populations studied. |
Specimen Type |
Blood |
Container |
Lavender Top Tube |
Collection Instructions |
Container/Tube: Lavender Top tube Specimen: 7 mL whole Blood ( 7 mL min) Transport Temperature: Room Temperature Stability: Maintain at Room Temperature or Refrigerated |
Transport Instructions |
Room Temperature |
Specimen Stability |
Maintain at Room Temperature or Refrigerated |
Methodology |
Sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution |
Days Performed |
TAT: 4-8 Days |
Performing Laboratory |
LabCorp |
CPT |
81381 LOINC Code: 13299-3 |
PDM |
225201 |
Desired Epic Build HLA B*58:01, Allopurinol Hypersensitivity
Cerner Primary Mnemonic: | HLA B*58:01 | ||||||||||||
PDM | 225201 | ||||||||||||
Informatics - Workgroup | Molecular-send outs | ||||||||||||
Synonyms * | HLAB58 | ||||||||||||
Display Name * | HLA B*58:01, Allopurinol Hypersensitivity | ||||||||||||
Order Entry Specimen Sources * | |||||||||||||
Order Entry Specimen Types |
Blood
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Ordering info (EPIC SmartText) | Allopurinol associated SCAR (severe cutaneous adverse drug reaction) including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has been shown to be associated with the human leukocyte antigen (HLA) B*58:01 of the major histocompatibility complex (MHC). The MHC family of genes codes for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T-cell receptors to elicit an immune response. The presence of the HLA B*58:01 allele increases the susceptibility to allopurinol SCAR in several populations studied. | ||||||||||||
IP Orderable | Yes | ||||||||||||
OP Orderable | Yes | ||||||||||||
AOEs * | |||||||||||||
AP AOEs | |||||||||||||
Special History | No | ||||||||||||
Build Comments | |||||||||||||
Filter * | genetics | ||||||||||||
Procedure Category Change | |||||||||||||
Cerner Results
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Current Actual EPIC Build as of 10/28/2024
Procedure Id | 115423 | ||||||||||||||||||||||||
Pdm | 225201 | ||||||||||||||||||||||||
Order Display Name | HLA B*58:01, Allopurinol Hypersensitivity | ||||||||||||||||||||||||
Procedure Name | HLA B*58:01 | ||||||||||||||||||||||||
Procedure Master Number | LAB11554 | ||||||||||||||||||||||||
Short Procedure Name | HLA B*58:01 | ||||||||||||||||||||||||
Category Code | 15.0 | ||||||||||||||||||||||||
Category Code Record Name | LAB CYTOGENETICS ORDERABLES | ||||||||||||||||||||||||
Synonyms | HLAB58 | ||||||||||||||||||||||||
Clinically Active | Yes | ||||||||||||||||||||||||
Orderable | Yes | ||||||||||||||||||||||||
Performable | Yes | ||||||||||||||||||||||||
Filter Genomics | Generic Genomics Procedure | ||||||||||||||||||||||||
Reference Link Url | https://labs.northwell.edu/epic/test/115423 | ||||||||||||||||||||||||
Ordering Instructions | |||||||||||||||||||||||||
Default Specimen Type | Blood | ||||||||||||||||||||||||
Specimen Type Pick List | Blood | ||||||||||||||||||||||||
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Specimen Source Pick List | Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous | ||||||||||||||||||||||||
Specimen Source Default - Male | Blood, Venous | ||||||||||||||||||||||||
Specimen Source Default - Female | Blood, Venous | ||||||||||||||||||||||||
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Order Questions | ["3045300170", "3045300171", "3045300173"] | ||||||||||||||||||||||||
Order Questions Record Name | NH IP HOME COLLECT DATE NH IP HOME COLLECT DAYS NH IP HOME COLLECT MEDICALLY NECESSARY | ||||||||||||||||||||||||
Inpatient Order Questions | ["3048500000"] | ||||||||||||||||||||||||
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Order Specific Question Override | Yes | ||||||||||||||||||||||||
Inpatient Question Override | |||||||||||||||||||||||||
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Edp Amb Order Specific Questions Record Name | NH IP PATIENT COMPLETED CONSENT | ||||||||||||||||||||||||
Edp Ip Order Specific Questions Record Name | NH IP PATIENT COMPLETED CONSENT | ||||||||||||||||||||||||
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Ip Orderable | 1 | ||||||||||||||||||||||||
Op Orderable | 1 | ||||||||||||||||||||||||
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EPIC Components (results)
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