Dihydropyrimidine Dehydrogenase (DPYD), 3 Variants for 5-FU Toxicity

Synonyms

  • DIHYDROPYRIMIDINE DEHYDROGENASE (DPYD)
  • LAB11553

Cerner Name

Dihydropyrimidine Dehydrogenase (DPYD)

Clinical Info

Predict risk of dose-related toxicity to 5-FU therapy
Informed Consent for Genetic Testing (Required for NY patients)

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

3 mL whole blood. (1 mL min)

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender (EDTA)
   Alternate: Pink (K2EDTA), or yellow (ACD Solution A or B).
Specimen: 3 mL whole blood. (1 mL min)


Informed Consent for Genetic Testing (Required for NY patients)

Transport Instructions

Refrigerated.

Specimen Stability

3 Days Room Temperature
14 Days Refrigerated
30 Days Frozen

Methodology

Polymerase Chain Reaction/Fluorescence Monitoring

Days Performed

TAT: 6 -11 Days

Performing Laboratories

ARUP Laboratories

CPT

81232

PDM

1759409

Results
Component Name Base Name Common Name External Name
DPYD SPECIMEN DPYDSPEC DPYD SPECIMEN DPYD Specimen
DPYD PHENOTYPE DPYDPHEN DPYD PHENOTYPE DPYD Phenotype
DPYD INTERPRETATION DPYD DPYD INTERPRETATION DPYD Interpretation
DPYD EER DIHYDROPYRIMIDINE DEHYDROGENASE DPYDEERDD DPYD EER DIHYDROPRYRIMIDINE EER Dihydropyrimidine Dehydrogenase
DPYD ALLELE 1 DYPDALLELE1 DPYD ALLELE 1 DPYD Allele 1
DPYD ALLELE 2 DYPDALLELE2 DPYD ALLELE 2 DPYD Allele 2

Result Interpretation

See Report

Forms
Molecular-send outs LAB11553 build edit