Direct detection of hemoglobin A, S, and C. This test is most useful for prenatal diagnosis of an at-risk fetus. This test can also be used for diagnosis of a symptomatic patient or carrier testing for a healthy adult.
Specimen Type
Container
Sterile
Collection Instructions
Container/Tube: Sterile leak-proof container Specimen: 20 mL amniotic fluid collected in sterile transport tube, or 30 mg direct chorionic villi, or 20 mL amniotic fluid collected in each of two T-25 flasks, or 20 mL cultured cells collected in each of two T-25 flasks Minimum Volume 10 mL amniotic fluid • 15 mg chorionic villi • 10 mL cultured cells Transport Temperature: Room Temperature Stability: Room temperature: 48 hours Refrigerated: Unacceptable Frozen: Unacceptable Collection Instructions Amniotic fluid: Collect 10-20 cc of amniotic fluid in a sterile plastic container.
Chorionic Villus Sample (CVS): Collect 15-30 mg of chorionic villi in a sterile container. Add 2-3 mL of sterile saline or tissue culture medium.
Cultured Cells: Ship two 100% confluent T-25 flasks filled with growth media. Ship at room temperature. Do not refrigerate or freeze. Call lab for additional requirements for prenatal testing. Indicate source of cells: Amniotic Fluid (AF) or Chorionic Villus Sample (CVS). Please send Maternal Cell Contamination Study, with this test. A separate tube of maternal blood (EDTA) must be drawn in order to rule out maternal contamination of the fetal sample
Transport Instructions
Room Temperature
Specimen Stability
Room temperature: 48 hours Refrigerated: Unacceptable Frozen: Unacceptable Collection Instructions Amniotic fluid: Collect 10-20 cc of amniotic fluid in a sterile plastic container.
Chorionic Villus Sam
Methodology
Polymerase Chain Reaction (PCR) This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Days Performed
Performing Laboratory
Quest Diagnostics' Nichols Institute, Inc. - Chantilly
