Ceramides, P

Synonyms

  • CERAMIDES, PLASMA
  • LAB11313

Cerner Name

Ceramides, P

Clinical Info

Evaluating for the risk of major adverse cardiovascular events within the next 1 to 5 years
MI-Heart Ceramides is a blood test that measures risk for adverse cardiovascular events and quantifies plasma ceramides. Plasma ceramides are predictors of adverse cardiovascular events resulting from unstable atherosclerotic plaque.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 mL EDTA plasma ( 0.5 mL min)

Container

Lavender Top Tube

Collection Instructions


Collection Container/Tube: Lavender top (EDTA)
Specimen : 1 mL EDTA Plasma (0.5 mL min)
Transport Temperature: Frozen
Collection Instructions: Freeze within 8 hours.
Patient Preparation: Patients should not be receiving Intralipid because it may cause false-elevations in measured ceramides

Transport Instructions

Specimen Stability

8 Hours Room Temperature
1 Day Refrigerated
30 Days frozen

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

TAT: 3-10 Days

Performing Laboratories

Mayo Clinic Laboratories

CPT

0119U
LOINC Code: 93883-7

PDM

1859767

Results
Component Name Base Name Common Name External Name
CERAMIDE (16:0) CERAMIDE160 CERAMIDE 160 Ceramide (16:0)
CERAMIDE (18:0) CERAMIDE180 CERAMIDE 180 Ceramide (18:0)
CERAMIDE (24:1) CERAMIDE24 CERAM24 Ceramide (24:1)
CERAMIDE (16:)/(24:0) CERAMIDE1624 CERAMINE 16 240 Ceramide (16:)/(24:0) ratio
CERAMIDE (18:0)/(24:0) CERAMIDE1824 CERAM1824RT Ceramide (18:0)/(24:0) ratio
CERAMIDE (24:1)/(24:0) CERAMIDE2424 CERAM2424RT Ceramide (24:1)/(24:0) ratio
CERAMIDE SCORE CERAMIDESCO CERAMSC MI-Heart Ceramide Risk Score

Result Interpretation

MI-Heart Ceramide Risk Score:
0-2 Lower risk
3-6 Moderate risk
7-9 Increased risk
10-12 Higher risk
Ceramide (16:0): 0.19-0.36 mcmol/L
Ceramide (18:0): 0.05-0.14 mcmol/L
Ceramide (24:1): 0.65-1.65 mcmol/L
Ceramide (16:0)/(24:0): <0.11
Ceramide (18:0)/(24:0): <0.05
Ceramide (24:1)/(24:0): <0.45
 
Reference values have not been established for patients who are <18 years of age.
 
Note: Ceramide (24:0) alone has not been independently associated with disease and will not be reported.

Forms
Chemistry LAB11313 build edit