Thyroid Cancer Mutation Panel

Synonyms

  • LAB11303
  • THYCANPL
  • THYROID CANCER MUTATION PANEL

Cerner Name

Thyroid Cancer Mutation Panel

Clinical Info

Thyroid Cancer Mutation Panel - The thyroid mutation panel assesses for all 8 of the most common mutations or rearrangements 
associated with thyroid neoplasia.

Specimen Sources

Abdominal Wall Alveoli Amniotic Sac Ankle, Left Ankle, Right Appendix Ascend Colon Autopsy Axilla, Left Axilla, Right Back, Lower Back, Upper Bladder Blood, Cord Brain, Amygdala Brain, Basal Ganglia Brain, Cerebellum Brain, Cerebral Cortex Brain, Hypothalamus Brain, Medulla Brain, Pons Breast, Left Breast, Left Central Breast, Right Breast, Right Central Buttock, Left Buttock, Right Cervix Cheek Cheek, Left Cheek, Right Chin Colon Colon, Cecum Diaphragm Ear, Left Ear, Right Fallopian Tube, Left Fallopian Tube, Right Fetus Foot, Left Foot, Right Forearm, Left Forearm, Right Forehead Foreskin Gallbladder Hand, Digit Left Hand, Digit Right Hand, Left Hand, Right Heart Hip, Right Kidney, Left Kidney, Right Knee, Left Knee, Right Large Intestine, Left/Descending Colon Large Intestine, Rectum Larynx Leg, Left Leg, Right Lip, Lower Lip, Upper Liver Lung, Left Lower Lobe Lung, Left Upper Lobe Lung, Right Lower Lobe Lung, Right Middle Lobe Lung, Right Upper Lobe Mediastinum Meninges/Dura Misc Naris, Left Naris, Right Nasal/Nasopharynx Neck Nose Oral Cavity Oropharynx Ostomy Pouch Ovary, Left Ovary, Right Pancreas Penis Pericardium Placenta Prostate Retroperitoneum Sacral Scalp Scrotum Shoulder, Left Shoulder, Right Sigmoid Colon Small Intestine, Duodenum Small Intestine, Ileum Small Intestine, Jejunum Spinal Cord Spine, Cervical Spine, Lumbar Spleen Stomach Sympathetic Ganglion Testicular Appendage Testis, Left Testis, Right Thigh, Left Thigh, Right Thoracic Throat Thymus Thyroid Toe, Left Toe, Right Tongue Trachea Transverse Colon Ureter, Left Ureter, Right Urethra Vas Deferens, Left Vas Deferens, Right Vulva Wrist, Left Wrist, Right Show more...

Specimen Types

Tissue

Specimen Volume

4 tissue slides- 6 FNA slides

Container

Fluid

Collection Instructions

Container/Tube: Formalin-fixed, paraffin-embedded tissue block
 
Specimen:   4 tissue slides- 6 FNA slides
(2 tissue slidesʉۢ 4 FNA slides min)
 Alternative Specimen(s)  Needle washing (see instructions) 
Collection Instructions Needle washings in alcohol-based fixative (e.g. CytoLyt® or formalin-fixed, paraffin-embedded tissue block FNA or FFPE specimens are acceptable for the assay.All specimens must be accompanied with Pathology report. All FFPE specimens will be examined by a pathologist for confirmation and adequacy. Macrodissection if warranted is performed in the lab.
 

Transport Instructions

Room Temperature

Specimen Stability

FNA or FFPE
  5 Years Room Temperature or Refrigerated
  Unacceptable  Frozen

Methodology

 
Includes
BRAF Mutation Analysis, Papillary Thyroid Cancer; RAS Mutation Analysis, Thyroid Cancer; RET/PTC Rearrangement, Thyroid Cancer; PAX8/PPAR[gamma] Translocation, Thyroid Cancer

Days Performed

Sunday - Saturday
 
Report available: 6 - 8 days

Performing Laboratories

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

CPT

81445

PDM

1759542

Results

Component Name Base Name Common Name External Name
RET/PTC1 RETPTC1 RET PTC1 RET/PTC1
THYROID CANCER MUTATATION PANEL SPECIMEN SOURCE THYCANCERSRC THYROID CANCER MUTATATION PANEL SPECIMEN SOURCE Spec Source:
RET/PTC3 RETPTC3 RET PTC3 RET/PTC3
PAX8/PPARG PAX8PPARG PAX8 PPARG PAX8/PPARG
BRAF GENE TARGETED MUTATION ANALYSIS BRAF BRAF GENE TARGETED MUTATION ANALYSIS BRAF Mutation
HRAS MUTATION HRASMUT HRAS MUTATION HRAS Mutation
KRAS MUTATION KRASMUT KRAS MUTATION KRAS Mutation
NRAS MUTATION NRASMUT NRAS MUTATION NRAS Mutation
BLOCK/SPECIMEN ID BLOCKSPECID BLOCK SPECIMEN ID Block/Specimen ID

Result Interpretation

BRAF Mutation Analysis, Papillary Thyroid Cancer

 

BRAF Mutation Not detected


RAS Mutation Analysis, Thyroid Cancer
 

HRAS Mutation Not detected
KRAS Mutation Not detected
NRAS Mutation Not detected


RET/PTC Rearrangement, Thyroid Cancer
 

RETPTC1 Not detected
RETPTC3 Not detected


PAX8/PPAR[gamma] Translocation, Thyroid Cancer
 

PAX8/PPAR gamma Not detected

 

Forms

Molecular-send outs LAB11303 build edit