Interleukin 28B

Synonyms

  • IL28B
  • INTERLEUKIN 28B POLYMORPHISM
  • LAB11218

Cerner Name

Interleukin 28B

Clinical Info

Predicting responsiveness of genotype 1 hepatitis C viral infections to combined pegylated-interferon and ribavirin-based therapies.
This test does not detect variants other than the rs12979860 single-nucleotide variant.
A previous bone marrow transplant from an allogenic donor will interfere with testing. 

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

3 mL whole blood (0.5 mL min)

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender-top (EDTA) tube
Specimen: 3 mL Whole Blood (1mL min)  In original tube  DO NOT ALIQUOT
Additional Information:
1. Specimens are preferred to be received within 4 days of collection. Extraction will be attempted for specimens received after 4 days, and DNA yield will be evaluated to determine if testing may proceed.
2. To ensure minimum volume and concentration of DNA is met, the preferred volume of blood must be submitted. Testing may be canceled if DNA requirements are inadequate.

Transport Instructions

Room Temperature

Specimen Stability

4 Days Room Temperature
4 Days Refrigerated
4 days Frozen

Methodology

Real-Time Polymerase Chain Reaction (PCR) With Allelic Discrimination Analysis.

Days Performed

TAT:  4-8 Days

Performing Laboratories

Mayo Medical Laboratories

CPT

81283
LOINC Code: 60279-7

PDM

5960145

Results
Component Name Base Name Common Name External Name
IL28B GENOTYPE IL28B INTERLEUKIN 28B GENOTYPE IL28B Genotype
IL28B PHENOTYPE IL28B INTERLEUKIN 28B PHENOTYPE IL28B Phenotype
INTERLEUKIN 28B POLYMORPHISM RESULT IL28BPOLYMOR INTERLEUKIN 28B POLYMORPHISM RESULT Interleukin 28B Polymorphism Result
INTERLEUKIN 28B INTERPRETATION IL28BINT INTERLEUKIN 28B INTERPRETATION Interleukin 28B Interpretation
INTERLEUKIN 28B ADDITIONAL INFORMATION IL28BADDL INTERLEUKIN 28B ADDITIONAL INFORMATION Interleukin 28B Additional Information
INTERLEUKIN 28B METHODOLOGY IL28BMETH INTERLEUKIN 28B METHODOLOGY Interleukin 28B Methodology
INTERLEUKIN 28B REFERENCES IL28BREF INTERLEUKIN 28B REFERENCES Interleukin 28B Disclaimer
IL28B DIRECTOR REVIEW IL28BDR IL28B DIRECTOR REVIEW Interleukin 28B Reviewed by

Result Interpretation

See Report

Forms
Immunology LAB11218 build edit