Glutathione, Total

Synonyms

• GLUTATHIONE, TOTAL
• LAB11214

Cerner Name

Glutathione, Total

Clinical Info

Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Container

Acd/Yellow

Collection Instructions

Container/Tube: Yellow ACD -B or ACD-A tube
Specimen: 500 uL Whole Blood (100uL min)
8 ml tube must have minimum 4.5ml whole blood
6 ml tube must have minimum 3.0ml whole blood
Transport Temperature: Room Temperature
Stability: 14 Days Room Temperature or Refrigerated
Unacceptable- Frozen
Collection: Allow ACD Tubes to fill completely; gently invert 8 - 10 times.

Specimen Volume

500 uL Whole Blood (100uL min)

Transport Instructions

Room Temperature

Specimen Stability

14 Days Room Temperature or Refrigerated
Unacceptable- Frozen
Collection: Allow ACD Tubes to fill completely; gently invert 8 - 10 times.

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Days Performed

TAT: 5-8 Days

Performing Laboratory

LabCorp Burlington

CPT

82978
 
LOINC Code: 2383-8

PDM

2059732

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms