Mexiletine Level

Synonyms

  • LAB11146
  • MEXILETINE LEVEL, SERUM

Cerner Name

Mexiletine

Clinical Info

Assessing achievement of optimal therapeutic concentrations
 
Assessing potential toxicity

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

Container

Red Top Tube

Collection Instructions

Specimen Type: Serum Red
Patient Preparation: Samples should only be collected after patient has been receiving mexiletine for at least 3 days. Trough concentrations should be collected just before administration of the next dose.
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions:
1. Samples should only be collected after patient has been receiving mexiletine for at least 3 days.
2. Draw blood immediately before next scheduled dose.
3. Centrifuge within 2 hours of draw and aliquot to remove serum from spun RBCs.
Specimen Minimum Volume: 0.5 mL
Specimen Stability Information:
Specimen TypeTemperatureTimeSpecial Container
Serum RedRefrigerated (preferred)28 days
 Ambient 28 days
 Frozen 28 days

Transport Instructions

Specimen Stability

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

Monday through Saturday

Performing Laboratories

Mayo Clinic Laboratories in Rochester

CPT

80299

PDM

5900985

Results

Component Name Base Name Common Name External Name
MEXILETINE MEXIL MEXILETINE Mexiletine

Result Interpretation

Trough Value
0.5-2.0 mcg/mL: Therapeutic concentration
>2.0 mcg/mL: Toxic concentration

Forms

Tox/TDM LAB11146 build edit