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Voltage-Gated Potassium Channel (VGKC) Antibody with Reflex to LGI1 and CASPR2 Screen and Titer

Test Catalog Information

Test Catalog Synonyms
EPIC Synonyms VGKC Ab with Reflex to LGI1 and CASPR2 Screen and Titer
VGKCRFX
Cerner Primary MnemonicVGKC Ab with Reflex to LGI1 and CASPR2 Screen and Titer
EPIC Display NameVoltage-Gated Potassium Channel (VGKC) Antibody with Reflex to LGI1 and CASPR2 Screen and Titer
Allscripts (AEHR) Order Name

VGKC Ab with Reflex to LGI1 and CASPR2 Screen and Titer

Sunrise Clinical Manager (SCM) Order Name

LGKC Ab w/Reflex to LGI1 & CASPR2

EPIC Inpatient Orderable Yes
EPIC Outpatient Orderable Yes
Cerner Results VGKCAB
CASPR2 Ab IgG Screen by IFA
LGI1ABGSCN
CASPR2 Ab IgG Titer by IFA
LGI1 Ab IgG Titer by IFA
Clinical Info

Screening test for voltage-gated potassium channel (VGKC) antibody receptor complex-associated autoantibodies with test reflex to CASPR2 and LGI1 antibodies. Antibodies are associated with acquired neuromyotonia, limbic encephalitis, painful neuropathy, Morvan syndrome, and rare tumors (eg, thymoma, small-cell lung cancer).

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold To[ Tube Specimen: 4 mL serum ( 0.5 mL min) Transport Temperature: Refrigerated Separate serum from cells within 1 hour.

Transport Instructions

Refrigerated

Specimen Stability

3 Days Room Temperature Refrigerated : 2 weeks Frozen: 1 Month

Methodology

Quantitative Radioimmunoassay/Semi-Quantitative Indirect Fluorescent Antibody
 
If VGKC is Indeterminate or Positive, LGI1 Antibody IgG and CASPR2 Antibody IgG will be added. If LGI1 antibody IgG is positive, then LGI1 antibody IgG titer will be added. If CASPR2 antibody IgG is positive, then CASPR2 antibody IgG titer will be added. Additional charges apply.

Days Performed

TAT 2 - 9 days Set up Tuesdays

Performing Laboratory

ARUP Laboratories

CPT

83519 LOINC Code: 41871-5

PDM

1759386

Desired Epic Build Voltage-Gated Potassium Channel (VGKC) Antibody with Reflex to LGI1 and CASPR2 Screen and Titer

Cerner Primary Mnemonic: VGKC Ab with Reflex to LGI1 and CASPR2 Screen and Titer
PDM 1759386
Informatics - WorkgroupImmunology
Synonyms *VGKC Ab with Reflex to LGI1 and CASPR2 Screen and Titer
VGKCRFX
Display Name *Voltage-Gated Potassium Channel (VGKC) Antibody with Reflex to LGI1 and CASPR2 Screen and Titer
Order Entry Specimen Sources *
Order Entry Specimen Types
Blood
Specimen Navigator Specimen Types
Specimen Navigator Specimen Sources
Specimen Navigator Short Name
Ordering info (EPIC SmartText)Screening test for voltage-gated potassium channel (VGKC) antibody receptor complex-associated autoantibodies with test reflex to CASPR2 and LGI1 antibodies. Antibodies are associated with acquired neuromyotonia, limbic encephalitis, painful neuropathy, Morvan syndrome, and rare tumors (eg, thymoma, small-cell lung cancer).
IP Orderable Yes
OP Orderable Yes
AOEs *

AP AOEs
Special History No
Build Comments
Filter *
Procedure Category Change
Cerner Results

Result DescResult displayResult PDM
VGKCAB VGKCAB 1559857A
CASPR2 Ab IgG Screen by IFA CASPR2 Ab IgG Screen by IFA 1759245A
LGI1ABGSCN LGI1ABGSCN 1759386A
CASPR2 Ab IgG Titer by IFA CASPR2 Ab IgG Titer by IFA 1759245B
LGI1ABGTR LGI1 Ab IgG Titer by IFA 1759386B

Current Actual EPIC Build as of 10/28/2024

Procedure Id 114634
Pdm 1759386
Order Display Name Voltage-Gated Potassium Channel (VGKC) Antibody with Reflex to LGI1 and CASPR2 Screen and Titer
Procedure Name LGKC AB W/REFLEX TO LGI1 & CASPR2
Procedure Master Number LAB11122
Short Procedure Name LGKC AB W/REFLEX TO LGI1 & CASPR2
Category Code 1.0
Category Code Record Name LAB BLOOD ORDERABLES
Synonyms VGKC AB WITH REFLEX TO LGI1 AND CASPR2 SCREEN AND TITER VGKCRFX
Clinically Active Yes
Orderable Yes
Performable Yes
Filter Genomics
Reference Link Url https://labs.northwell.edu/epic/test/114634
Ordering Instructions
Default Specimen Type Blood
Specimen Type Pick List Blood
Specimen Type List
Op Specimen Type List
Specimen Source Pick List Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous
Specimen Source Default - Male Blood, Venous
Specimen Source Default - Female Blood, Venous
Specimen Source List
Op Specimen Source List
Ip Lab Test Components For Report
Op Lab Test Components For Report
Order Questions []
Order Questions Record Name
Inpatient Order Questions []
Inpatient Order Questions Record Name
Order Specific Question Override
Inpatient Question Override
Location Restrict List Ip
Location Restrict List Ip Record Name
Location Restrict List Include Ip
Location Restrict List Op
Location Restrict List Op Record Name
Location Restrict List Includes Op
Edp Amb Order Specific Questions Record Name
Edp Ip Order Specific Questions Record Name
Edp Ip Specimen Source Blood, Venous Blood, Central Line Blood, Arterial Blood, Capillary
Edp Op Specimen Source
Edp Ip Specimen Type Blood
Edp Op Specimen Type
Derived Edp Ip Buttons S Blood, Central Line Blood, Venous Blood, Capillary Blood, Arterial
Derived Edp Ip Buttons T Blood
Derived Edp Op Buttons S
Derived Edp Op Buttons T
Ip Orderable 1
Op Orderable 1
EPIC OP AOEs

EPIC IP AOEs

EPIC Components (results)

Component IDComponent NameBase NameCommon NameExternal NameCerner Result PDM
3047805239 VOLTAGE-GATED K CHANNEL AB VGKCHANAB VOLTAGE GATED K CHANNEL AB 1559857A
3047801659 CASPR2 AB IGG SCREEN BY IFA CASPR2 CASPR2 AB IGG SCREEN BY IFA 1759245A
3047803275 LGI1 AB IGG SCREEN BY IFA LG1ABIGGSC LGI1 AB IGG SCREEN BY IFA 1759386A
3047801660 CASPR2 AB IGG TITER BY IFA CASPR2 CASPR2 AB IGG TITER BY IFA 1759245B
3047803276 LGI1 AB IGG TITER BY IFA LG1ABIGGT LGI1 AB IGG TITER BY IFA 1759386B