CMV Resistance-5 Antiviral Meds

Cytomegalovirus (CMV) Resistance-5 Antiviral Me

The CMV Resistance measures: Maribavir, Letermovir, Ganciclovir, Foscarnet, Cidofovir Human Cytomegalovirus (CMV) infections are a major cause of morbidity and mortality among immunocompromised patients. 

Blood

Lavender Top Tube

Container/Tube: Lavender (EDTA) Top Tube Specimen: 2 mL plasma (0.2 mL min)   Samples must be received within 6 days of collection unless frozen

Refrigerated

7 Days room Temperature 7 Days Refrigerated 60 Days Frozen

PCR followed by genotypic sequencing

TAT: 3 - 5 Days Patient outcomes depend on effective prophylaxis and treatment with antiviral therapies, including maribavir, letermovir, cidofovir, ganciclovir, valganciclovir and foscarnet. Additionally, letermovir is approved specifically for prophylactic use in hematopoietic stem cell transplant (HSCT) patients. Proper patient management requires rapid detection of resistance. Laboratory testing should be used to confirm the occurrence of drug resistance, as treatment modification based solely on clinical suspicion may result in added toxicity and increased complexity in patient management. The CMV Resistance: Maribavir, Letermovir, Ganciclovir, Foscarnet, Cidofovir sequencing assay is designed to detect identified mutations in the UL54, UL56 and UL97 genes of CMV. The use of genotypic sequencing offers a rapid turnaround time, a broad range of antiviral resistance information, and the ability to provide information concerning new drugs as they become available

Eurofins-Viracor

87910 x 3

235701